Calcium Succinate 159389-75-0 Manufacturer Exporter Supplier MEDIOCON INC

 

 

 

Calcium Succinate Manufactured by MEDIOCON INC

 

   Name: Calcium Succinate

CAS No:   159389-75-0

Molecular Weight:  174.17 g/mol

Molecular formula:  CaC₄H₄O₄.H₂O

Synonyms: Calcium Succinate Anhydrous Monohydrate or Succinic acid calcium salt monohydrate or Butanedioic acid, calcium salt monohydrate.

Appearance:  white fine powder. 

 Solubility :  soluble in water and slightly soluble in ethanol, ether acetone and glycerol.

Use :

Calcium succinate is used in various applications:

- Food Industry: As a food additive, acidity regulator, and preservative (E355)

- Pharmaceuticals: As an excipient in tablet formulations

- Cosmetics: In skincare products for its moisturizing and pH-regulating properties

- Agriculture: As a fertilizer or soil conditioner

 

Benefits of calcium succinate include [1][2][3]:

- pH Regulation: Helps maintain pH balance in products

- Antimicrobial Properties: Inhibits microbial growth

- Moisturizing: Attracts and retains moisture in skin and products

Consult relevant guidelines and regulations for specific use cases.

 

 How is  Calcium Succinate manufactured by MEDIOCON INC Synthesized?

Calcium succinate is synthesized through a reaction between succinic acid and calcium hydroxide or calcium carbonate. Here's a simplified process:

- Dissolve Succinic Acid: Dissolve succinic acid in water.

- Add Calcium Source: Add calcium hydroxide or calcium carbonate to the solution.

- Stir and React: Stir the mixture until the reaction is complete, forming calcium succinate and water or carbon dioxide as by-products.

 

Alternatively, industrial production involves reacting succinic acid with calcium chloride, followed by heating, filtering, and crystallization.¹

What are the different  dosage forms  of   Calcium Succinate Manufactured  by  MEDIOCON INC?

Calcium succinate is available in various dosage forms, including:

- Tablets: Oral tablets for supplementation or therapeutic use

- Capsules: Oral capsules for supplementation or therapeutic use

- Powder: Powdered form for use in food products, cosmetics, or pharmaceuticals

- Granules: Granular form for use in food products or pharmaceuticals

These dosage forms cater to different applications and industries, such as food, pharmaceuticals, and cosmetics.

 How Calcium Succinate Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Calcium succinate dosage forms are prepared through various processes:

- Tablets and Capsules: Mixing calcium succinate with excipients, followed by granulation, compression, or encapsulation.

- Powder and Granules: Milling or grinding calcium succinate into desired particle sizes, then blending with other ingredients if needed.

 

Manufacturing processes may involve [1][2]:

- Wet Granulation: Mixing calcium succinate with binders and solvents to form granules.

- Direct Compression: Compressing calcium succinate powder into tablets.

- Encapsulation: Filling calcium succinate powder into capsules.

Quality control measures ensure consistency and purity in the final product.

What are the appropriate Dosage forms of Calcium Succinate Manufactured  by  MEDIOCON   INC?                

Calcium succinate is available in various dosage forms, including [1][2]:

- Oral Tablets: For supplementation or therapeutic use

- Capsules: For oral administration

- Powder: For use in food products, cosmetics, or pharmaceuticals

- Granules: For food products or pharmaceutical applications

The choice of dosage form depends on the intended use, industry, and desired release profile.

When should Calcium Succinate Manufactured by MEDIOCON INC be taken?

Calcium succinate is typically taken as directed by a healthcare professional or according to product instructions. Here are some general guidelines:

- With Meals: Often taken with meals to enhance absorption

- As Supplements: Usually taken once or twice daily, depending on individual needs

- Food Fortification: Added to food products as needed

 

Consult a healthcare professional for specific advice on taking calcium succinate, especially if you have underlying medical conditions or take other medications [1][2].

 What are the effects And Side effects of Calcium Succinate Manufactured by MEDIOCON INC?

Calcium succinate is generally considered safe when consumed in food amounts. However, there isn't enough reliable information to determine its safety or potential side effects when used in medicinal amounts.¹

 

Some possible uses of calcium succinate include:

- Symptoms of Menopause: Relief from menopause symptoms

- Obesity: Weight management

- Rheumatoid Arthritis (RA): Management of RA symptoms

- Sexual Problems: Addressing sexual satisfaction issues

 

If you're considering taking calcium succinate supplements, consult a healthcare professional to discuss potential benefits and risks.

 

In contrast, metoprolol succinate, a different medication, has known side effects like² ³ ⁴:

- Common Side Effects: Tiredness, dizziness, depression, diarrhea, shortness of breath, bradycardia, and rash

- Serious Side Effects: Severe heart problems, respiratory issues, and depression

Always consult a healthcare professional before taking any medication or supplement.

  How is Calcium Succinate Manufactured by MEDIOCON  INC  Tested Qualitatively?

Calcium succinate is tested qualitatively using several methods.

- Flame Test: Calcium ions produce an orange-red flame color.

- Precipitation Reaction: Adding ammonium oxalate to a calcium solution forms a white precipitate of calcium oxalate.

- Carbonate Test: Adding ammonium carbonate to a calcium solution forms a white precipitate of calcium carbonate, which is soluble in acetic acid.

These tests help identify the presence of calcium ions in a sample.

   Which tests are performed on Calcium Succinate Manufactured by  MEDIOCON INC ?

Several tests are performed on calcium succinate to ensure its quality and purity:

- Identification Tests: Flame test, precipitation reaction, and carbonate test to confirm calcium presence

- Purity Tests: Assay, heavy metals, and impurities testing

- Physical Tests: Particle size, bulk density, and flowability testing

- Microbiological Tests: Total viable count, yeast and mold count, and pathogens testing

 

Specific tests may include [1][2]:

- Assay: Titration or HPLC to determine calcium succinate content

- Heavy Metals: Atomic absorption spectroscopy (AAS) or inductively coupled plasma (ICP) testing

- Related Substances: HPLC or TLC testing for impurities

What are the challenges in Manufacturing of Banana Extract Manufactured by MEDIOCON   INC API?

Manufacturing banana extract API faces several challenges:

- Raw Material Availability: Limited supply of banana plants, primarily grown for fruit, causing fluctuations in availability and pricing.

- Processing Difficulties: Labor-intensive extraction and cleaning processes require specialized equipment, increasing production costs.

- Quality Control: Variability in harvesting and processing leads to inconsistent fiber quality, affecting suitability for various applications.

- Environmental Impact: Chemical treatments generate waste, necessitating careful management to minimize pollution.

- Market Perception: Banana fiber products are relatively niche, requiring consumer education to promote awareness and adoption.

- Pest Susceptibility: Banana plants are vulnerable to pests, impacting raw material quality and availability.

These challenges impact efficiency, quality, and market viability, requiring improved extraction techniques, processing methods, and supply chain management.

What are the challenges in manufacturing of Calcium Succinate Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing calcium succinate dosage forms comes with several challenges, including¹ ² ³:

- Stability Issues: Ensuring the stability of calcium succinate throughout the manufacturing process and shelf life.

- Poor Solubility: Calcium succinate's solubility can be a challenge, affecting bioavailability.

- Raw Material Sourcing: Sourcing high-quality calcium succinate and excipients can be difficult.

- Regulatory Compliance: Meeting stringent regulatory requirements for excipient manufacturing, transportation, and storage.

- Quality Assurance: Ensuring integrity and purity throughout the supply chain.

- Cost and Supply Chain Management: Balancing cost considerations with high-quality excipients.

- Manufacturing Process Failures: Deficiencies in manufacturing processes can lead to defective products.

- Particle Aggregation: Solid particles can aggregate, causing sedimentation and inconsistent dosing.

To overcome these challenges, manufacturers can leverage advanced technologies, such as 3D printing and nanotechnology, and collaborate with regulatory agencies and excipient suppliers.

What is the Packing for Calcium Succinate Manufactured by MEDIOCON INC?

Calcium Succinate is typically packed in various sizes, including:

- 25Kg Bag: Commonly used for industrial and pharmaceutical applications

- 20 Kg Bag: Also available for specific requirements

- 100g, 500g, and 2Kg: Smaller packs for laboratory and research purposes

- Drum: Used for larger quantities, often in pharmaceutical manufacturing

The packaging may vary depending on the supplier and intended use

What is shelf life Of Calcium Succinate Manufactured by MEDIOCON INC? 

Calcium Succinate typically has a shelf life of 3 years when stored properly in a tightly closed container in a cool, well-ventilated area, away from incompatible substances like oxidizing agents.

What should the label claim for Calcium Succinate Manufactured by MEDIOCON INC   Include?

The label claim for Calcium Succinate should include the following information¹ ² ³:

- Statement of Identity: Clearly indicate the product name, such as "Calcium Succinate"

- Amount of Active Ingredient: Specify the amount of Calcium Succinate, usually in milligrams (mg) or percentage (%)

- Form of Active Ingredient: Indicate the form of Calcium Succinate, such as powder or capsules

- Health Claims: Include approved health claims, like "Calcium may reduce the risk of osteoporosis"

- Nutrient Content Claims: Specify nutrient content, such as "Good source of calcium"

- Serving Size: Clearly state the serving size and number of servings per container

- Daily Value: Include the percentage of Daily Value (%DV) for calcium

 

Some examples of label claims for Calcium Succinate include⁴:

- "Good source of calcium": Indicates the product contains a significant amount of calcium

- "Calcium for healthy bones and teeth": Highlights the role of calcium in maintaining bone health

- "Diets high in calcium may reduce the risk of osteoporosis": Approved health claim linking calcium to osteoporosis prevention

Where can Calcium Succinate Manufactured by MEDIOCON INC are procured?

Calcium Succinate Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Calcium Succinate Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Calcium Succinate Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Calcium Succinate Manufactured by MEDIOCON INC product, regardless of the procurement source.