Frankincense Oil 8016-36-2 Manufacturer, exporter, supplier by MEDIOCON INC

 

 

 

Frankincense Oil Manufactured by MEDIOCON INC

 Name: Frankincense Oil

CAS No : 8016-36-2

Molecular Weight:  N/A (as it is a mixture) / 289.5 g/mol (sometimes cited for industrial, mixed constituents)

Molecular formula:  

C63H98O6cap C sub 63 cap H sub 98 cap O sub 6

𝐶63𝐻98𝑂6

(Commonly cited for technical grade) / Frequently reported as

C20H32Ocap C sub 20 cap H sub 32 cap O

𝐶20𝐻32𝑂

(representing major components like pinene)

·       Synonyms: Olibanum Oil, Oil of Frankincense, Gum Olibanum, Boswellia Carterii Oil, Boswellia Serrata Oil

·       Appearance: Colorless to pale yellow, slightly viscous liquid. 

·        Solubility :   Insoluble in water; soluble in alcohol, oils, and organic solvents

Use :

·        

• Aromatherapy: Used for its calming, woody, and spicy scent to reduce stress and promote relaxation.
• Skincare: Used in creams and lotions to fight acne, reduce scars, and minimize signs of aging (wrinkles, fine lines).
• Medicinal: Used for anti-inflammatory properties, to soothe muscle aches, and as an expectorant to clear respiratory passages.
• Fragrance/Industrial: Used in soaps, lotions, and perfumes. 

Physical Properties: 

• Density: 0.862–0.889 g/mL at 25°C
• Boiling Point: $\sim$140°C
• Flash Point:

47--95∘C47 -- 95 raised to the composed with power C

47--95∘C

 

 How is  Frankincense Oil  manufactured by MEDIOCON INC Synthesized?

MEDIOCON INC likely produces their Frankincense Oil through steam distillation or CO2 extraction of crushed Boswellia tree resin, standard methods for creating essential oils, rather than true chemical synthesis, involving heating the resin with steam to release volatile compounds, followed by cooling and separation. While the exact proprietary process isn't public, this natural extraction from dried tree sap (resin) is how genuine frankincense oil is made, focusing on isolating key components like alpha-pinene. 

General Process for Frankincense Oil Production (Likely Used by MEDIOCON):

1.    Resin Collection: Tapping Boswellia trees (like Boswellia carteri) yields milky sap, which dries into hard, aromatic resin "tears".

2.    Crushing: These dried resin pieces are crushed into smaller fragments or powder.

3.    Extraction:

1.             Steam Distillation: The crushed resin is placed in a distiller, heated with steam, and the steam carries the essential oil vapor, which is then cooled and collected.

2.             CO2 Extraction: Supercritical carbon dioxide is used to extract the oil, preserving more delicate compounds.

4.    Separation & Bottling: The oil is separated from the water (hydrosol) and then bottled, often in dark glass. 

Why "Synthesis" is Misleading:

·       Frankincense oil is a natural product, and manufacturers like MEDIOCON aim to capture its complex natural chemistry, not create it from basic chemicals in a lab (which would be true chemical synthesis). 

What are the different  dosage forms  of   Frankincense Oil  Manufactured  by  MEDIOCON INC?

Based on the product portfolio of Mediocon Inc, which operates as a global supplier of chemicals and ingredients (including essential oils), the Frankincense oil is primarily manufactured in liquid form. 

While they specialize in bulk essential oils, the typical, high-quality Frankincense oil produced (often from Boswellia Serrata) is available in the following formats for industrial and commercial use: 

·       Liquid Essential Oil (Bulk): Pure liquid, often obtained via steam distillation, commonly stored in GI Cans, GI Barrels, or Aluminum Bottles for industrial use.

·       Aromatic/Fragrance Oil (Liquid): Used for aromatherapy and cosmetic applications. 

Mediocon Inc acts as a supplier to various industries, providing these in bulk for further processing into products like lotions, soaps, and perfumes. 

 How Frankincense Oil  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Based on the provided search results, Frankincense Oil is produced by companies using advanced

steam distillation of Boswellia serrata tree resin, often in state-of-the-art facilities. While the search results mention Kelvin Natural Mint Pvt. Ltd. and other India-based, and not specifically a company named "MEDIOCON INC," the general industrial manufacturing of frankincense oil involves the following processes: 

Manufacturing of Frankincense Oil 

• Source Material: Resin from Boswellia trees (e.g., Boswellia Serrata).
• Extraction Method: The oil is primarily produced through steam distillation, which creates a pure, therapeutic-grade oil.
• Advanced Extraction: Some advanced methods include supercritical

CO2cap C cap O sub 2

𝐶𝑂2

extraction, which is used to obtain higher yields (approx. 21% yield) and to prevent the oxidation of unstable components.

• Quality Control: The process involves monitoring to ensure purity, often producing oil with a base to medium note, high effectiveness, and a shelf life of up to two years. 

Dosage Form Preparation (General Process)
For therapeutic applications, such as in pharmaceutical or supplement industries, the oil is processed into various forms: 

• Softgel/Capsules: The frankincense oil is dissolved in medium-chain fatty acid triglycerides or other vegetable oils, followed by the addition of amphiphilic substances, and encapsulated.
• Solid Dosage Forms (Tablets/Capsules):
1. Mixing: The essential oil is mixed with adsorbents/absorbents (e.g., calcium silicate, silicon dioxide, magnesium aluminum silicate).
2. Surfactant Addition: The mixture is combined with a surfactant.
3. Excipient Blending: The mixture is combined with excipients, such as fillers/diluents, binders, and lubricants.
4. Compression: The final mixture is converted into tablets or encapsulated.
• Nanoemulsions: Prepared using the water titration method, where frankincense oil is mixed with surfactant/co-surfactant mixtures (e.g., Tween 20: Transcutol P) and water, followed by probe sonication. 

What are the appropriate Dosage forms of Frankincense Oil  Manufactured  by  MEDIOCON   INC?                

Based on the product portfolio of Mediocon Inc, which specializes in essential oils, herbal extracts, and API intermediates, Frankincense Oil is typically manufactured and supplied in the following forms: 

·       Essential Oil (Liquid): 100% Pure/Therapeutic grade intended for aromatherapy, skincare, and cosmetic applications.

·       Herbal Extract (Powder/Liquid): Used as raw material for further processing into tablets or capsules. 

Key Characteristics & Applications:

·       Packaging: Supplied in bulk or specific volumes (e.g., typically 5ml to 100ml for retail, or higher for industrial use).

·       Usage: Generally used for topical application (diluted) and diffusion.

·       Quality Standards: Products are manufactured in compliance with WHO GMP guidelines and are ISO 9000:2008 certified. 

When should Frankincense Oil  Manufactured by MEDIOCON INC be taken?

Based on general product information for therapeutic-grade, steam-distilled frankincense essential oil (derived from Boswellia serrata), such as that manufactured by companies like MEDIOCON INC, the oil is intended for topical application (diluted) and aromatherapy to support relaxation, skincare, and stress relief. 

It is generally advised that this type of frankincense essential oil should not be ingested. 

Here is when and how it should be used:

Recommended Times and Uses

·       Daily Wellness & Stress Relief: Use daily as needed for relaxation, meditation, or to manage stress. This can be done by diffusing 3–5 drops in a diffuser or by adding a drop to the palm, rubbing hands together, and inhaling.

·       Skincare Routine: Apply as part of a morning or night routine to support skin health (e.g., reducing appearance of fine lines or scars). It should be diluted with a carrier oil (such as jojoba or coconut oil) before applying.

·       Before Sleep: Used in a diffuser or added to a body lotion before bed to aid in relaxation and induce sleep.

·       Topical Application: Apply 1-2 times daily to skin for specific concerns, such as joint or muscle discomfort, after proper dilution. 

 What are the effects And Side effects of Frankincense Oil  Manufactured by MEDIOCON INC?

Potential Effects and Benefits

·       Skin Health: It is used for its astringent properties to tone skin, reduce the appearance of wrinkles, fine lines, and sun spots, and to help heal acne.

·       Stress Relief and Aromatherapy: Inhaling the aroma is used to reduce anxiety, depression, anger, and stress, and to aid with insomnia.

·       Anti-inflammatory and Pain Relief: It may help reduce joint pain and swelling associated with arthritis and muscle pain.

·       Respiratory Support: It is known to help clear up congestion and alleviate symptoms of bronchitis and asthma.

·       Immune System Boost: It is thought to have antiseptic properties. 

Potential Side Effects

·       Skin Irritation: Topical application of undiluted oil can cause redness, itching, and dermatitis.

·       Gastrointestinal Distress: If ingested, it may cause stomach pain, nausea, and diarrhea.

·       Allergic Reactions: Rare, but potential reactions include difficulty breathing and skin rashes.

·       Blood Thinning: It may have blood-thinning effects, which could increase the risk of bleeding in individuals with bleeding disorders or those on anticoagulant medications. 

  How is Frankincense Oil  Manufactured by MEDIOCON  INC  Tested Qualitatively?

Mediocon Inc. likely tests their Frankincense Oil qualitatively using advanced analytical techniques like Gas Chromatography-Mass Spectrometry (GC-MS) to identify key chemical components (terpenes, ethers) and ensure purity, alongside physical tests (smell, appearance, viscosity) and potential biological assays (antimicrobial activity), ensuring consistency and adherence to industry standards for their pharma, food, and fragrance clients. 

Key Qualitative Testing Methods

1.    Gas Chromatography-Mass Spectrometry (GC-MS):

·       Purpose: This is the gold standard for identifying the unique chemical fingerprint of essential oils, revealing the types and amounts of compounds like α-pinene, limonene, and caryophyllene.

·       How it works: The oil is vaporized and separated (GC), then fragmented and identified by mass (MS).

2.    Physical & Organoleptic Tests:

·       Appearance & Odor: Checks for clarity, color, and the characteristic woody, spicy aroma, ensuring it matches the expected profile.

·       Refractive Index & Specific Gravity: Measures physical properties for consistency.

3.    Microbiological & Biological Assays (Potentially):

·       Antimicrobial Testing: Methods like well diffusion or broth microdilution test effectiveness against bacteria or fungi, indicating oil potency.

·       Cell-based Assays: For research, testing effects on cancer cells (like MDA-MB-231) using MTT assays, though this is more R&D.

4.    Purity & Adulteration Checks:

·       GC-MS & Isotope Ratio Mass Spectrometry: Detects adulterants or synthetic additives, a critical factor for quality. 

·       Which tests are performed on Frankincense Oil  Manufactured by  MEDIOCON INC ?

Based on the provided search results, Mediocon Inc is an Aurangabad-based supplier and manufacturer of Essential Oils, including Frankincense, serving the pharmaceutical, nutraceutical, and cosmetic industries

. While specific, batch-level testing data for Mediocon Inc is not explicitly detailed in the text, high-quality Frankincense oil suppliers in India, including those with similar profiles, typically perform the following quality control tests: 

• Gas Chromatography-Mass Spectrometry (GC/MS) Analysis: This is the primary test used to determine the chemical composition (e.g., levels of

αalpha

𝛼

-pinene, limonene,

αalpha

𝛼

-thujene) and to ensure the purity of the oil.

• Physical Property Testing:
• Density/Specific Gravity: Often checked at 25°C, with typical values for frankincense oil around 0.870.
• Refractive Index: Usually tested to be within a specific range, such as 1.465 to 1.485.
• Optical Rotation: Measures the rotation of polarized light, a key indicator of authenticity.
• Sensory Evaluation: Organoleptic testing for aroma (woody, spicy), color, and appearance.
• Acid Value and Ester Value: Titration methods used to measure the acid content and ester content, which help in assessing purity.
• Solubility/Miscibility in Ethanol: Tests the miscibility of the oil in ethanol to check for adulteration.
• Heavy Metal and Pesticide Residue Analysis: To comply with safety standards for herbal extracts. 

What are the challenges in manufacturing of Frankincense Oil  Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing frankincense oil faces challenges in ensuring consistent quality due to varying raw materials (species, location), choosing the right extraction method (hydrodistillation risks degradation, solvent extraction risks residues), and standardizing the final product's potent boswellic acid content, making dosage tricky; specific challenges for MEDIOCON INC aren't detailed, but general issues include thermal stability, purification, and achieving desired bioavailability for therapeutic use, often requiring advanced techniques like nanoemulsions. 

Key Manufacturing Challenges:

1.    Raw Material Variability:

·       Different Boswellia species yield oils with vastly different boswellic acid (BA) profiles, affecting efficacy.

·       Geographical origin and harvesting practices alter resin composition.

2.    Extraction Method Selection:

·       Hydrodistillation/Steam Distillation: Can degrade heat-sensitive compounds, alter scent, and reduce active ingredients.

·       Organic Solvent Extraction: May leave harmful solvent residues, making the oil unsuitable for pharmaceutical/nutraceutical use.

·       Cold Pressing: Might yield lower nutraceutical content.

3.    Quality & Standardization:

·       Commercial products show huge differences in BA content, making it hard to get consistent pharmacological effects.

·       Ensuring consistent extraction of specific BAs (like AKBA) is complex.

4.    Dosage & Bioavailability:

·       The complex composition makes precise dosage difficult; BAs need to reach target sites effectively.

·       Poor water solubility limits absorption, requiring advanced formulation (e.g., nanoemulsions) for better delivery, notes Frontiers in Pharmacology.

5.    Thermal & Chemical Stability:

·       Gum resin and extracted oil undergo degradation at high temperatures, impacting quality. 

. 

What is the Packing for Frankincense Oil  Manufactured by MEDIOCON INC?

While specific packaging for MEDIOCON INC's Frankincense Oil isn't detailed in general search results, manufacturers of similar oils typically use GI Cans, HDPE Drums, Aluminum Bottles, or Galvanized Drums for bulk quantities (like 25kg, 180kg) and often smaller, dark glass bottles for retail, ensuring protection from light and air for freshness. 

Typical Packaging Options for Frankincense Oil Manufacturers:

·       Bulk: GI Cans, GI Barrels, Aluminum Bottles, HDPE Drums, Galvanized Drums

·       Retail/Smaller Quantities: Dark glass bottles (amber or cobalt blue) are standard for protecting essential oils from light degradation. 

To find MEDIOCON INC's specific packaging:

·       Check their official website or product listings for detailed specifications.

·       Contact them directly for their standard packaging options. 

What should the label claim for Frankincense Oil  Manufactured by MEDIOCON INC   Include?

For Frankincense Oil from MEDIOCON INC, label claims should focus on purity, source, processing (cold-pressed), benefits (aroma, cleaning, potential therapeutic uses), storage, and certifications (organic, non-GMO), adhering to regulatory guidelines (like FDA, USDA) for essential oils, highlighting natural essence, potentially listing key components like limonene, and clearly stating usage instructions, ensuring it reflects the oil's quality and intended use, whether cosmetic or culinary. 

Here's a breakdown of key elements to include:

Mandatory Information:

1.    Product Name: Frankincense Oil (or Cold-Pressed Lemon Essential Oil).

2.    Brand Name: MEDIOCON INC.

3.    Net Quantity: (e.g., 15mL, 30mL).

4.    Ingredients: 100% Pure Frankincense Oil (or Lemon Peel Oil).

5.    Manufacturer Details: MEDIOCON INC, address, contact info.

6.    Batch/Lot Number & Expiry/Best Before Date.

7.    Storage Instructions: Store in a cool, dark place, tightly sealed, away from heat.

8.    Warning/Caution: For external use only (if cosmetic); keep out of reach of children; avoid contact with eyes; dilute with carrier oil. 

Recommended Claims & Details:

·       Source/Process: "Extracted from fresh Lemon Peels," "Cold-Pressed for Purity".

·       Purity: "100% Pure & Natural," "Therapeutic Grade" (if applicable).

·       Aroma/Scent: "Uplifting Citrus Aroma," "Fresh Lemon Scent".

·       Benefits (Use cautiously & back with science): "Promotes Cleanliness," "Refreshing," "Natural Fragrance," "Aids in aromatherapy".

·       Key Component: May list "Contains Limonene".

·       Certifications: USDA Organic, Non-GMO, Vegan (if applicable).

·       Usage Suggestions: "For diffusers," "For DIY cleaning solutions," "Add to soaps/lotions". 

Where can Frankincense Oil  Manufactured by MEDIOCON INC are procured?

Frankincense Oil  Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Frankincense Oil  Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Frankincense Oil  Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Frankincense Oil  Manufactured by MEDIOCON INC product, regardless of the procurement source.