Jojoba Oil 61789-91-1 Manufacturer Supplier Exporter, MEDIOCON INC

 

 

 

Jojoba Oil  Manufactured by MEDIOCON INC

 

   Name: Jojoba Oil  

CAS No: 61789-91-1

Molecular Weight: 500-700 g/mol

Molecular formula:  NA

Synonyms : Jojoba bean oil, Jojoba liquid wax, Jojobae oelum

 

Appearance : Jojoba oil is typically a clear, golden-yellow liquid with a mild, nutty odor, though refined versions can be colorless and odorless; it's known for its light, non-greasy texture and is actually a liquid wax, similar to skin's natural sebum, making it an excellent moisturizer that penetrates easily and doesn't spoil quickly. 

  

 Solubility : Jojoba oil is insoluble in water but highly soluble in other oils, fixed oils, and many organic solvents like alcohol, ether, and acetone, due to its liquid wax ester structure similar to human sebum, making it excellent for skin/hair products and as a lubricant. It blends well with essential oils and other cosmetic esters but doesn't mix with water-based formulas. 

 

Uses : Jojoba oil is a versatile moisturizer, makeup remover, and hair treatment, prized for mimicking natural skin oils (sebum) and being non-comedogenic (won't clog pores), making it great for all skin types, including oily or acne-prone skin, to soothe inflammation, balance oil, and fight bacteria while providing antioxidants (Vitamins A, E) for anti-aging, sunburn relief, and scar healing, also used in hair/scalp care, as a massage/cuticle oil, and even for pet paws.  

 

  How Jojoba Oil  is manufactured by MEDIOCON INC Synthesized?

Jojoba oil isn't typically "synthesized" but extracted from the seeds of the Simmondsia chinensis desert shrub, primarily through mechanical cold pressing, often followed by filtration and refining to create different grades (golden or colorless). While some complex chemical processes exist for research or specific derivatives, commercial production relies on harvesting seeds, cleaning them, and pressing out the natural liquid wax esters, which are structurally similar to human sebum

 

 

What are the different  dosage forms of Jojoba Oil  Manufactured  by  MEDIOCON INC?

MEDIOCON INC is a manufacturer and supplier of nutraceuticals and pharmaceutical intermediates. The search results indicate that Jojoba oil, which they supply as a raw material, is suitable for use in the formulation of a variety of dosage forms, including solid orals, liquid orals, oral care products, and topicals. 

 

 

 How Jojoba Oil  Manufactured by MEDIOCON INC Dosage Forms are prepared?

MEDIOCON INC is a manufacturer and wholesaler, and while general methods for creating jojoba oil dosage forms exist, specific details regarding their proprietary preparation processes are not publicly available. 

Generally, the manufacturing of jojoba oil dosage forms involves the following steps:

Jojoba Oil Extraction

The process starts with the extraction of crude jojoba oil (which is actually a liquid wax) from the seeds of the Simmondsia chinensis plant. 

·       Pressing: Seeds are fed into an expeller press, which crushes them to force out the oil.

·       Filtering: The expelled oil, which is initially cloudy, is passed through a filter press to remove solid particles.

·       Refining: A natural powdered absorbent is often used to clarify the oil to its finished state (either a golden color with a mild aroma, or further refined to be colorless and odorless). 

Dosage Form Preparation

Once the oil is refined, it is used as a primary ingredient in various cosmetic and pharmaceutical dosage forms. The specific preparation method depends entirely on the desired final product, such as: 

·       Emulsions and Nano-emulsions: These are prepared by mixing the oily phase (jojoba oil and other oil-soluble ingredients) with an aqueous phase (water and water-soluble ingredients like propylene glycol and surfactants). The mixture is emulsified using high-speed mixers and homogenizers to create a stable product.

·       Gels/Emulgels: Gelling agents like Carbopol or hydroxypropyl methylcellulose are added to the emulsion phase to increase viscosity and create a gel consistency. The pH is often adjusted for stability and effectiveness.

·       Creams and Lotions: Similar to emulsions, these involve blending the oil with water and emulsifiers to achieve the desired consistency.

·       Pure Oil: The oil may simply be bottled after final filtration as a standalone product (e.g., as a carrier oil or a direct-application moisturizer).

 

 

What are the appropriate Dosage forms of Jojoba Oil  Manufactured  by  MEDIOCON   INC?

MEDIOCON INC is listed as a manufacturer and wholesaler, but information specifically regarding the dosage forms of Jojoba Oil they produce is not publicly available in the search results. 

General applications of Jojoba oil in the industry include:

·       Topical applications, such as in lotions, creams, ointments, shampoos, conditioners, and general body oils. It is widely used in personal care and cosmetic products for its moisturizing and emollient properties.

·       Oral care products.

·       Potential use in solid and liquid oral dosage forms (though ingestion of large amounts is not recommended due to potential toxicity). 

 

When should Jojoba Oil  Manufactured by MEDIOCON INC be taken?

Jojoba oil is for external use only and should never be "taken" or ingested orally. It is not digestible by the human body and contains a chemical, erucic acid, which can cause serious side effects, including heart damage, if consumed. 

The product manufactured by MEDIOCON INC, like all other jojoba oils, is intended for topical application as part of a skincare or haircare routine. 

When to Apply Jojoba Oil Topically

Jojoba oil can be incorporated into your daily personal care regimen. 

For Skin Care:

·       As a daily facial moisturizer: Apply a few drops to clean skin in the morning and/or night.

·       In your routine: It should generally be applied after cleansing, toning, and serums, but before a heavier moisturizer, due to its consistency.

·       As a makeup remover: Use it with a cotton pad to gently remove makeup and cleanse pores.

·       For specific conditions: It can be applied to chapped skin, sunburns, or areas affected by acne, eczema, or psoriasis to soothe inflammation and promote healing. 

For Hair Care:

·       As a leave-in conditioner/serum: Apply a few drops to the ends of damp or dry hair to smooth frizz and add shine.

·       As a scalp treatment: Massage into the scalp before shampooing (leaving it on for 25-30 minutes) to help with dandruff and moisturize the scalp. 

Before using jojoba oil for the first time, it is recommended to perform a patch test on a small area of skin (e.g., your inner elbow) and wait 24 hours to ensure you do not have an allergic reaction.

 

 

 

 What are the effects And Side effects of Jojoba Oil  Manufactured by MEDIOCON INC?

The effects and side effects of Jojoba Oil manufactured by MEDIOCON INC are consistent with general jojoba oil products, which is safe for topical use but unsafe for oral consumption due to the presence of erucic acid. Specific product information for MEDIOCON INC's oil beyond general properties was not available in the search results. 

Effects and Benefits of Topical Jojoba Oil

Jojoba oil is widely used in cosmetic and pharmaceutical applications due to its similarity to the natural sebum produced by human skin. 

·       Moisturization: It is a potent emollient and humectant that helps hydrate the skin and hair, locking in moisture and preventing dryness without leaving a greasy residue.

·       Acne Control: It helps regulate the skin's natural oil production and is non-comedogenic (does not clog pores), making it suitable for acne-prone skin.

·       Anti-inflammatory and Antimicrobial: It has anti-inflammatory and antibacterial properties that can soothe irritated skin conditions like eczema, psoriasis, and sunburn, and help fight off certain bacterial and fungal infections.

·       Wound Healing and Anti-aging: The antioxidants and vitamins (E, B-complex) in jojoba oil can help accelerate wound healing, promote collagen synthesis, and reduce the appearance of fine lines, wrinkles, and scars.

·       Hair Health: It can condition hair, help manage dandruff and dry scalp, prevent hair loss, and add shine and strength to hair strands. 

Potential Side Effects and Risks

Jojoba oil is considered "likely safe" for most people when applied to the skin. However, some side effects and precautions exist: 

·       Allergic Reactions: Although rare because it is hypoallergenic, some individuals may experience skin irritation, rashes, hives, or itching. A patch test is recommended before widespread use.

·       Internal Consumption is Unsafe: Jojoba oil should never be taken by mouth as it contains erucic acid, a chemical that can cause serious health problems, including heart damage.

·       Use during Pregnancy: While topical application is generally considered safe during pregnancy and breastfeeding, it is recommended to consult a healthcare provider before use.

·       Interaction with Other Products: It can enhance the penetration of other topical medications, which may increase their potency or the risk of irritation if mixed with strong active ingredients like retinoids. 

 

 

 

 How is Jojoba Oil  Manufactured by MEDIOCON  INC  Tested Qualitatively?

In general, the quality and purity of Jojoba oil in manufacturing are typically tested using industry-standard qualitative and quantitative methods to assess its physical and chemical properties, often compared against benchmarks like those set by the International Jojoba Export Council (IJEC) or the American Oil Chemists' Society (AOCS). 

Common qualitative and quantitative tests used in the industry include:

·       Organoleptic Assessment: Pure, refined jojoba oil is typically a clear, light golden color (or colorless if bleached) and has a mild, nutty aroma or is odorless. Any significant deviation in color or a strong, rancid smell could indicate impurities or degradation.

·       Low-Temperature Test: Jojoba oil is a liquid wax and will remain liquid at temperatures where many other vegetable oils might solidify. If the oil solidifies at around 10°C (50°F) or above, it is likely adulterated.

·       Peroxide Value: This test measures the concentration of peroxides and hydroperoxides, which are indicators of oxidative rancidity (oil damage). A low peroxide value indicates high stability and freshness.

·       Iodine Value: This value measures the degree of unsaturation (double bonds) in the oil's fatty acid chains. Jojoba oil has a high iodine number compared to other vegetable oils, which confirms its unique chemical structure.

·       Acid Value: This test determines the amount of free fatty acids present, which can indicate the oil's age and quality. A low acid value is desirable.

·       Refractive Index: This physical property is measured to verify the oil's purity against established standards for jojoba oil.

·       Gas Chromatography (GC) Analysis: This instrumental method provides a detailed profile of the fatty acid and fatty alcohol composition, which is the primary way to confirm the oil's identity and detect adulteration. 

MEDIOCON INC, as a manufacturer, likely employs several of these standard methods to ensure its Jojoba oil meets quality specifications. 

 

 

 

   Which tests are performed on Jojoba Oil  Manufactured by  MEDIOCON INC ?

MEDIOCON INC, as a manufacturer and wholesaler of Jojoba oil, performs standard quality control tests to ensure the product meets industry and regulatory specifications. These tests are typical for commercial Jojoba oil and generally include: 

Physicochemical Property Tests 

These tests confirm the basic physical and chemical characteristics of the oil: 

·       Appearance and Odor: Checking for a clear, bright, pale yellow to golden yellow liquid that is free from rancid or foreign odors.

·       Specific Gravity: Measuring the density of the oil, typically within a range like 0.860-0.880 at 25°C.

·       Refractive Index: Measuring how light passes through the oil to confirm purity and concentration, often in the range of 1.445-1.475 at 20°C.

·       Moisture and Insoluble Impurities: Ensuring minimal water content and absence of solid impurities. 

Chemical Composition Tests

These tests help determine the purity, stability, and specific composition of the oil's fatty acids: 

·       Acid Value: Measures the amount of free fatty acids present, indicating age and quality, with lower values (e.g., ≤ 5.0 mgKOH/g) being ideal.

·       Saponification Value: Indicates the nature of the fatty acids in the fat (longer carbon chains result in a lower value). A typical range is 85.0-100.0 mgKOH/g.

·       Iodine Value: Measures the degree of unsaturation (double bonds) in the oil's fatty acids. Jojoba oil typically has a value of 80.0-95.0 mg/g.

·       Peroxide Value: A key indicator of oxidative rancidity and damage level, measuring peroxides and hydroperoxides formed during initial oxidation. Lower values (e.g., ≤ 10.0 Meq/kg at the time of production) indicate high stability.

·       Unsaponifiable Matter: Measures the percentage of components that do not hydrolyze with potassium hydroxide, typically 45.0-55.0% for Jojoba oil.

·       Fatty Acid Profile Analysis: Performed using Gas Chromatography (GC) to identify and quantify specific fatty acids (e.g., gadoleic, erucic, oleic, palmitic acids) to ensure it matches the unique profile of Simmondsia chinensis seed oil. 

Impurity and Safety Tests

·       Heavy Metals Analysis: Checking for trace elements such as lead (Pb) and arsenic (As) to meet safety standards.

·       Microbial Contamination: Testing for the presence of bacteria or fungi to ensure product safety and shelf life.

·       Pesticide Residues: Ensuring the oil is free from harmful pesticide residues. 

These tests align with industry standards set by organizations like the Cosmetic, Toiletry, and Fragrance Association (CTFA) to confirm the oil's identity, purity, and safety. Specific test results are usually detailed on the product's Certificate of Analysis (CoA), which can be obtained from MEDIOCON INC directly. 

 

 

 

 

What are the challenges in manufacturing of Jojoba Oil  by MEDIOCON  INC ’s Dosage forms?

Mediocon Inc primarily specializes in pharmaceutical intermediates, nutraceuticals, and industrial chemicals and does not appear to manufacture jojoba oil dosage forms. Therefore, there are no specific manufacturing challenges reported for them regarding this product. 

However, the general challenges in manufacturing dosage forms (e.g., creams, ointments, or oral solutions) that contain jojoba oil, which is a liquid wax, can be broadly categorized as: 

Formulation and Physicochemical Challenges

·       Immiscibility with water: Jojoba oil is a liquid wax that is insoluble in water, which presents significant challenges when developing water-based creams, lotions, or other aqueous pharmaceutical dosage forms. This requires the use of effective emulsifiers and stabilizers to create a uniform and stable product.

·       High lipophilicity: The high lipophilicity (oil-loving nature) of the oil makes it difficult to incorporate into non-lipid-based formulations, requiring specialized formulation techniques or excipients to ensure proper dispersion.

·       Viscosity control: Jojoba oil maintains its viscosity at high temperatures, but achieving the desired rheological properties (flow and consistency) for a specific dosage form (e.g., a pourable liquid vs. a thick cream) requires precise control during manufacturing.

·       Consistency and quality control: Ensuring a consistent quality of natural jojoba oil can be challenging, as the composition of natural oils may vary slightly depending on the source and extraction methods. This can impact the final product's stability and efficacy. 

Manufacturing and Processing Challenges

·       Extraction efficiency: While jojoba oil can be extracted efficiently, traces of solvents might remain if solvent extraction is used, which can affect the final oil's properties and purity. Mechanical pressing alone yields a lower amount of oil.

·       Incorporation into solid dosage forms: Incorporating a lipid like jojoba oil into solid dosage forms like tablets can be complex and may require specific techniques or novel excipients to ensure the tablet's stability, disintegration, and dissolution properties.

·       Packaging and stability: The high thermal and oxidative stability of natural jojoba oil (due to natural antioxidants) is a benefit; however, processed or refined oil may have lower stability and requires appropriate packaging and storage conditions to prevent rancidity or degradation. 

Regulatory Challenges

·       Regulatory compliance: As with any pharmaceutical product, dosage forms containing jojoba oil must meet stringent regulatory requirements (e.g., US FDA or EMA guidelines) for quality, safety, and efficacy, which can be a complex and time-consuming process.

·       Bioequivalence data: For generic topical or transdermal products, generating the required bioequivalence data can be a significant hurdle. 

 

 

                                                                 

What is shelf life Of Jojoba Oil  by MEDIOCON INC

The general shelf life for jojoba oil is 2 years (24 months), though specific product information for MEDIOCON INC indicates a typical shelf life of 18 months from the date of manufacturing when stored properly. 

Jojoba oil is actually a liquid wax, which makes it highly stable and resistant to going rancid compared to other carrier oils. Its shelf life can extend up to 5 years or even indefinitely if stored correctly. 

 

 

 

What should the label claim for Jojoba Oil  Manufactured by MEDIOCON INC Include?

For MEDIOCON INC's Jojoba Oil, the label should include the INCI name (Simmondsia Chinensis Seed Oil), its origin (Jojoba Plant), key benefits (moisturizing, skin-compatible like sebum, non-comedogenic, versatile), certifications (Organic, Virgin), and quality indicators (First Cold Press), alongside standard product details like volume, manufacturer info, and usage instructions for skin/hair care. 

 

 

 

Where can Jojoba Oil  Manufactured by MEDIOCON INC are procured?

Jojoba Oil  Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Jojoba Oil  Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Jojoba Oil  Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Jojoba Oil  Manufactured by MEDIOCON INC product, regardless of the procurement source.