Methionine,: 63-68-3; DL-Methionine: 59-51-8Manufacturer, exporter, supplier by MEDIOCON INC

 

 

 

              Methionine, Manufactured by MEDIOCON INC

 

 Name:   Methionine

CAS No  :  L-Methionine: 63-68-3; DL-Methionine: 59-51-8

Molecular Weight : 149.21 g/mol

Molecular formula: C₅H₁₁NO₂S

Synonyms

·       (S)-2-Amino-4-(methylthio)butanoic acid, L-alpha-Amino-gamma-methylmercaptobutyric acid, Met, M

·       Appearance: White crystalline powder or colorless to white lustrous plates with a faint odor (sometimes described as sulfurous).

·       Solubility: Sparingly soluble to soluble in water (solubility increases with temperature), soluble in dilute acids and alkali solutions, and very slightly soluble in alcohol

o   Uses : Essential amino acid (a precursor for cysteine, glutathione, and polyamines), involved in protein synthesis and methylation processes (DNA, RNA, proteins), and used as a nutrient supplement and flavoring agent

o   What are the appropriate Dosage forms of Methionine,, , acid, Manufactured  by  MEDIOCON   INC?                

Information regarding the specific methionine products manufactured by MEDIOCON INC could not be found in the search results.

However, methionine is widely available and generally manufactured in the following appropriate dosage forms by various pharmaceutical companies for both human and animal use: 

·       Capsules: An oral solid dosage form.

·       Tablets: Another common oral solid form.

·       Oral Solution/Liquid: Used for patients, particularly children, who have difficulty swallowing tablets or capsules, and to facilitate dose adjustment.

·       Powder (for oral suspension): Available as a powder mixture to be reconstituted with water before use, which helps with stability and taste.

·       Intravenous (IV) Solution: Used in hospital settings, often as part of a total parenteral nutrition (TPN) solution containing multiple amino acids and other ingredients. 

To determine the specific dosage form manufactured by MEDIOCON INC, it is recommended to directly check the company's product catalog or contact a representative using the Mediocon Inc contact information. 

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  How is Methionine,, , acid, Manufactured by MEDIOCON  INC  Tested Qualitatively?

While specific proprietary methods used by MEDIOCON INC are not publicly available, the qualitative testing of Methionine (an amino acid) in a manufacturing context generally involves standard pharmacopoeial and chemical analysis methods to confirm its identity and purity. 

Common qualitative methods for methionine and other amino acids include:

·       Colorimetric Tests: These are traditional wet chemistry methods. For methionine, the addition of sodium nitroprusside to an alkaline solution, followed by acidification, yields a red color, which is a specific qualitative test.

·       Chromatographic Techniques: Modern industrial and pharmaceutical quality control relies heavily on advanced analytical techniques to confirm identity and purity simultaneously.

o   High-Performance Liquid Chromatography (HPLC): This is commonly used for amino acid analysis. The sample is run through an HPLC column, and the resulting chromatogram is compared against a known standard. The retention time of the sample peak confirms the presence of methionine.

o   Thin Layer Chromatography (TLC): TLC can be used as a simpler, more rapid method for qualitative confirmation and to check for the presence of impurities.

·       Mass Spectrometry (MS): Often coupled with HPLC (LC-MS/MS), MS provides a highly specific method by detecting the exact mass-to-charge ratio of the methionine molecule and any potential impurities, offering unambiguous identification.

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   Which tests are performed on Methionine,, , acid, Manufactured by  MEDIOCON INC ?

Mediocon Inc., like other pharmaceutical manufacturers, performs a series of standard quality control (QC) tests on its Methionine product to ensure it meets specific quality and purity standards, likely based on pharmacopeial guidelines such as the European Pharmacopoeia (EP). 

While specific product documentation from Mediocon Inc. was not available in the search results, typical tests for a pharmaceutical grade amino acid like Methionine (or DL-Methionine) generally include: 

Standard Quality Control Tests

·       Appearance: Visual inspection for color and form (e.g., white crystalline powder or platelets).

·       Identification: Confirmatory chemical tests and infrared absorption spectroscopy to verify the substance is indeed Methionine.

·       Purity/Assay: Quantitative analysis (typically via methods like titration or High-Performance Liquid Chromatography (HPLC)) to ensure the Methionine concentration meets the specified percentage (e.g., 99.0% - 101.0%).

·       Clarity and Color of Solution: Testing to ensure that a specified solution of the product is clear and colorless.

·       pH value: Measurement of the pH of an aqueous solution to confirm it falls within the required range.

·       Loss on Drying: Determination of the amount of moisture and volatile matter in the sample.

·       Residue on Ignition: Measurement of the inorganic residue remaining after ignition, indicating minimal inorganic impurities.

·       Specific Impurity Limits: Testing for specific potential impurities such as:

o   Heavy metals (e.g., lead (Pb)).

o   Arsenic.

o   Sulphate.

o   Chloride.

o   Ammonium.

o   Other amino acids. 

What are the challenges in Manufacturing of Banana Extract Manufactured by MEDIOCON   INC API?

Manufacturing banana extract as an API involves challenges like securing consistent, quality raw material (bananas/peels), optimizing extraction for high yield/purity (especially removing impurities during scale-up), managing costs (substrate, operations, downstream processing), ensuring regulatory compliance (CPCB, CDSCO), and developing sustainable practices to handle biomass waste while meeting API quality targets like purity and particle size. 

Here are the key challenges:

Raw Material & Supply Chain:

·       Consistent Supply: Ensuring a steady, year-round source of high-quality banana biomass (peels, pseudostems, etc.) for uninterrupted production.

·       Biomass Variability: Natural variations in banana composition due to climate, soil, and pathogens can affect extract quality. 

Extraction & Purification (Downstream Processing):

·       Yield & Purity: Developing efficient, cost-effective methods to isolate target compounds (like flavonoids, phenolics) while removing unwanted substances.

·       Scale-Up Issues: Impurities present in small batches might become major issues during large-scale manufacturing, requiring process adjustments.

·       Separation Technologies: Effectively separating the API from the biomass using advanced techniques (e.g., continuous crystallization, liquid-liquid extraction) is complex. 

Quality & Regulatory Compliance:

·       Critical Quality Attributes (CQAs): Controlling parameters like purity, impurity profiles, water content, and particle size to meet API standards.

·       Regulatory Adherence: Meeting strict guidelines from bodies like CPCB, CDSCO, and adhering to environmental regulations (EMS, green chemistry). 

Process & Sustainability:

·       Cost-Effectiveness: Balancing high production, operation, and purification costs with market demands.

·       Waste Management: Handling large volumes of banana biomass waste sustainably to prevent environmental contamination.

·       Green Chemistry: Implementing eco-friendly solvents and catalysts (like ionic liquids) to reduce the environmental footprint. 

 

What is the Packing for Methionine,, , acid, Manufactured by MEDIOCON INC?

 

MEDIOCON INC is a wholesaler and manufacturer of nutraceutical and pharmaceutical ingredients. 

Based on typical industry practices for the bulk supply of amino acids, methionine is generally offered in packaging such as: 

·       25 kg cardboard or fiber HDPE drums with double plastic bags inside.

·       25 kg HDPE bags. 

The specific packaging size for the product manufactured by MEDIOCON INC would depend on whether it is a wholesale/industrial order or part of a final consumer product (e.g., tablets or smaller supplement bottles). MEDIOCON INC is listed as a supplier of L-Methionine in bulk (kilograms) on trade platforms, consistent with large-volume industrial packaging. 

To get the exact packaging details for a specific order, it is recommended to contact MEDIOCON INC directly via their website. 

What should the label claim for Methionine,, , acid, Manufactured by MEDIOCON INC   Include?

The label claim for a Methionine amino acid product manufactured by MEDIOCON INC must adhere to the labeling regulations set by the relevant regulatory body, such as the FDA in the United States, and include specific mandatory information. This information ensures the product is properly identified and safely used. 

Mandatory Label Information

The label must include the following general information: 

·       Statement of Identity: The common or usual name of the product (e.g., "Methionine" or "L-Methionine") and a statement identifying it as a "dietary supplement," "food additive," or other applicable description, depending on its intended use and classification.

·       Net Quantity of Contents: The amount of the product in the package by weight or volume.

·       Name and Place of Business: The name and address of the manufacturer, packer, or distributor (MEDIOCON INC).

·       Ingredient List: A list of all ingredients in descending order of predominance by weight. For amino acids, the specific form (e.g., L-methionine) should be listed.

·       Nutrition or Supplement Facts Panel:

o   For a dietary supplement, a "Supplement Facts" panel must list the name and quantitative amount by weight per serving of the methionine. The serving size and servings per container must also be listed.

o   For a food additive, a "Nutrition Facts" panel is generally required for conventional food products, but if only individual amino acids are present, protein content may not be declared. 

Required Claims and State

Where can Methionine,, , acid, Manufactured by MEDIOCON INC are procured?

Methionine,, , acid, Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Methionine,, , acid, Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Methionine,, , acid, Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Methionine,, , acid, Manufactured by MEDIOCON INC product, regardless of the procurement source.