Rice bran oil. 68553-81-1 Manufacturer, exporter, supplier by MEDIOCON INC

 

 

 

Rice bran oil. Manufactured by MEDIOCON INC

 Name: Rice bran oil.

CAS No : 68553-81-1

Molecular Weight : Approximately 876.6–900 g/mol (average triglyceride).

Molecular formula:  

As a natural mixture of triglycerides, it does not have a single fixed formula, but it is frequently represented by the formula for its main components, such as

C57H110O6C sub 57 H sub 110 O sub 6

C57H110O6

(approx. triglycerides) or

C18H32O2C sub 18 H sub 32 O sub 2

C18H32O2

·       (as a generic fatty acid representation).

·       Synonyms: Oryza Sativa (Rice) Bran Oil, Fats and Glyceridic oils, rice bran, Branoil, Edible Rice Bran Oil, Rice bran oil refined.

·       Rice bran oil.

·       Appearance: Light yellow to yellowish-brown, oily liquid.

·        Solubility :   Light yellow to yellowish-brown, oily liquid.

·       Use :

·        

·        

o   Culinary: High-temperature cooking, deep frying, and stir-frying due to a high smoke point (approx. 245–254°C).

o   Nutraceutical/Health: Rich in Gamma Oryzanol (a natural antioxidant), Vitamin E (tocopherols and tocotrienols), used to lower blood cholesterol.

o   Cosmetics: Used in lotions, creams, shampoos, and hair conditioners as a moisturizer, skin-conditioning agent, and emollient. 

Key Properties:

·       Density: 0.919 g/mL at 25 °C

·       Flash Point: > 250 °C

·       Composition: Contains roughly 38% monounsaturated, 37% polyunsaturated, and 25% saturated fatty acids. 

·       . 

 

 How is  Rice bran oil.Oil  manufactured by MEDIOCON INC Synthesized?

 

Based on the provided search results, there is no direct information detailing a specific Rice bran oil manufacturing, including by companies like MEDIOCON INC, isn't synthesis (creating new molecules) but rather extraction and refining from rice bran using solvents (like hexane) or pressing, followed by degumming, bleaching, deacidification, and deodorization to produce safe, clear edible oil, a process that isolates existing natural compounds like oryzanol. The core steps involve stabilizing bran, extracting crude oil, and refining it to remove impurities, retaining beneficial nutrients. 

Here's a breakdown of the typical process:

1.    Raw Material Preparation (Stabilization): Rice bran is cleaned, screened, and heated (steamed) to deactivate lipase enzymes, which would otherwise degrade the oil.

2.    Extraction:

1. Solvent Extraction (Most Common): The stabilized bran is sprayed with a solvent (like hexane) to dissolve the oil, forming a mixture (miscella). The solvent is then evaporated and recovered for reuse, leaving crude rice bran oil (CRBO).
2. Mechanical Pressing: Less common for high yields, oil is pressed out physically.

3.    Refining: The crude oil undergoes several stages to become edible:

0.    Degumming: Removes phospholipids (gums).

1.    Deacidification: Reduces free fatty acids (FFAs).

2.    Decolorization: Bleaches the oil to remove pigments.

3.    Deodorization: Removes odors and flavors using steam distillation.

4.    Dewaxing (Winterization): Removes waxes for clarity and stability at lower temperatures. 

What are the different  dosage forms  of   Rice bran oil.Oil  Manufactured  by  MEDIOCON INC?

Rice bran oil (RBO) appears in various forms, primarily as a liquid oil for cooking, but also as ingredients in cosmetics (liposomes, emulsions, gels, masks) for skin benefits and even as a component in pharmaceutical delivery systems (lipid-core nanocapsules); however, specific dosage forms for a product from "MEDIOCON INC" aren't detailed in these general search results, which highlight RBO's diverse applications beyond just edible oil, leveraging compounds like gamma-oryzanol. 

General Dosage Forms of Rice Bran Oil:

·       Edible Oil: The most common form, used as a cooking medium, sometimes blended with other oils.

·       Cosmetic Ingredients: Incorporated into:

o   Liposomes & Nanocapsules: For delivering bioactive compounds like gamma-oryzanol and ferulic acid for anti-aging.

o   Creams & Gels: As moisturizers and sunscreens due to its smooth texture and vitamin E content.

o   Masks: Used in DIY or commercial face masks for skin health.

·       Pharmaceutical/Nutraceutical: As a carrier or active ingredient in formulations like lipid-core nanocapsules for potential medicinal delivery. 

Regarding "MEDIOCON INC":

·       The provided search results discuss rice bran oil in general but do not specifically mention a company named "MEDIOCON INC" or its unique product formulations.

·       To find the specific dosage forms from MEDIOCON INC, you would need to:

o   Check their official website or product packaging.

o   Look for specific product names, as they likely market it for cooking or as a cosmetic ingredient. 

 How Rice bran oil.Oil  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Based on the provided search results, rice bran oil—such as the type potentially manufactured for industrial, cosmetic, or nutraceutical applications—undergoes a rigorous multi-stage manufacturing process to ensure purity, stability, and the retention of bioactive compounds like γ-oryzanol. The oil is primarily extracted from the outer layer of brown rice (bran) using solvent extraction, followed by a detailed refining process. 

Here is the breakdown of the manufacturing process and dosage form preparation:

1. Manufacturing Process (Extraction & Refining)

·       Stabilization (Pre-treatment): Fresh rice bran is heated (often above 100°C) using steam to inactivate the lipase enzyme, which prevents free fatty acid formation, which would otherwise ruin the oil.

·       Expansion/Extrusion: The bran is conditioned and passed through an extruder to create a porous, soft structure (pellets), which improves solvent penetration and increases oil yield.

·       Solvent Extraction: The stabilized, expanded bran is mixed with a food-grade solvent (usually n-hexane) to dissolve the oil, forming a mixture called "miscella".

·       Solvent Recovery & Crude Oil Separation: The miscella is heated in evaporators to vaporize and recover the hexane for reuse, leaving behind crude rice bran oil.

·       Refining (RBD - Refined, Bleached, Deodorized):

o   Degumming: Removal of phospholipids and gums using water or acid.

o   Dewaxing/Winterization: The oil is cooled (6-9°C) to crystallize the wax, which is then filtered out to ensure the oil remains clear.

o   Bleaching: Activated clay is used to remove pigments and impurities.

o   Deacidification/Deodorization: High-temperature vacuum steam distillation removes free fatty acids and odors, while preserving bioactive compounds like oryzanol. 

2. Preparation of Dosage Forms

Rice bran oil is utilized in various forms, particularly in skin care, hair care, and nutritional supplements. 

·       Liquid/Oral Form: The refined oil is packaged into food-grade bottles or, for therapeutic use, it may be processed for oral intake, often fortified with Vitamin E.

·       Solid Orals/Capsules: The oil is processed into soft gel capsules or other solid oral formulations, often in combination with other nutritional compounds.

·       Topicals (Creams/Lotions): The oil acts as an emollient and carrier oil, used in the formulation of anti-aging creams, lotions, and sunscreens (due to its γ-oryzanol content).

·       Liquisolid/Semisolid Formulations: The oil is incorporated into specialized pharmaceutical formulations, such as liquid-solid or semi-solid systems, to improve bioavailability. 

 What are the appropriate Dosage forms of Rice bran oil.Oil  Manufactured  by  MEDIOCON   INC?                

Based on the provided search results, there is no specific information connecting a company named "MEDIOCON INC" to the manufacturing of rice bran oil. The search results highlight major manufacturers like IMC (Riceen), Fortune, and Emami. 

However, based on general industry standards for high-quality, refined rice bran oil (often used for health and culinary purposes), the appropriate dosage forms and applications are:

Appropriate Forms and Applications of Rice Bran Oil

·       Liquid/Refined Oil (Edible): This is the most common form, typically used for cooking, frying, and salad dressing. It has a high smoke point (approx. 232°C/450°F).

·       Capsules/Supplements: Used for concentrated intake of oryzanol and tocotrienols for heart health.

·       Topical Application: Used in skincare products (lotions, creams) as a moisturizer and emollient, due to its richness in Vitamin E and antioxidants. 

Disclaimer: This information is for general knowledge and should not be taken as medical advice. Consult with a healthcare provider before using rice bran oil for any health condition.

When should Rice bran oil.Oil  Manufactured by MEDIOCON INC be taken?

Rice bran oil, including products manufactured by Mediocon Inc, is a versatile, heart-healthy cooking oil that should be used as part of a daily diet, particularly for high-heat cooking methods. It is ideal for frying, sautéing, stir-frying, and baking due to its high smoke point (around 450°F/232°C), which prevents it from breaking down at high temperatures. 

When and How to Use Rice Bran Oil

·       For Daily Cooking: It can be used as a direct, healthier replacement for regular vegetable or refined oils in everyday cooking.

·       For High-Heat Applications: It is excellent for deep-frying and stir-frying, as its light nature means less oil is absorbed into the food (up to 15-20% less), making meals less greasy and easier to digest.

·       For Salads and Baking: It has a mild, nutty flavor that makes it suitable for salad dressings and in baking.

·       As a Nutritional Supplement: It contains Gamma-Oryzanol and Vitamin E, which are known for antioxidant properties and cholesterol-lowering effects. 

Rice bran oil can be used daily in various cooking applications. Storing it in a cool, dry place away from direct sunlight helps maintain its quality. When using rice bran oil for its potential health benefits, such as supporting healthy cholesterol levels, it is most effective when integrated into a balanced diet. 

 What are the effects And Side effects of Rice bran oil.Oil  Manufactured by MEDIOCON INC?

Based on the product portfolio of Mediocon Inc, which specializes in supplying raw pharmaceutical materials, API intermediates, and specialty chemicals, their Rice bran oil.products are generally intended for commercial or manufacturing use. 

Canola oil, in general, is a refined vegetable oil with specific, often debated, health effects. The following information applies to the general characteristics of refined canola oil, as specific clinical trials for a "Mediocon Inc" brand-specific edible consumer product are not available in the search results. 

Effects (Potential Benefits)

·       Heart Health Support: Rice bran oil.is high in monounsaturated fats (MUFA) and low in saturated fat. It contains plant sterols, which can inhibit cholesterol absorption, potentially reducing LDL ("bad") cholesterol by 10-15%.

·       Good for Cooking: It has a high smoke point (approx. 468–475°F / 200°C), making it suitable for deep frying, sautéing, and stir-frying.

·       Nutrient Profile: It is a source of Vitamin E and K.

·       Reduced Inflammation: Some studies indicate that it can reduce joint stiffness and tenderness. 

Potential Side Effects and Risks

·       Inflammation and Oxidative Stress: Several animal studies have linked high consumption of Rice bran oil.to increased inflammation and oxidative stress.

·       Memory Issues: Research suggests that chronic, high consumption of Rice bran oil.may damage memory and increase body weight.

·       Genetic Modification (GMO): Most Rice bran oil.is derived from genetically modified seeds.

·       Chemical Refining: Rice bran oil.is highly refined, processed with heat, and sometimes hexane (a solvent), which may reduce its antioxidant levels.

·       Blood Thinning: Due to high omega-3 fatty acid content, it may act as a blood thinner, potentially increasing bruising or bleeding, particularly if consumed in high amounts.

·       Allergic Reactions: While rare, allergic reactions (shortness of breath, hives, skin rash) can occur in sensitive individuals. 

Manufacturing Considerations (Mediocon Inc)

According to the company profile, Mediocon Inc is a "global supplier of high-quality chemicals and ingredients" that complies with WHO GMP guidelines and ISO 9000:2008 certification. This suggests they focus on purity and quality control in their production of raw ingredients for food, pharmaceuticals, and other industries. 

  How is Rice bran oil.Oil  Manufactured by MEDIOCON  INC  Tested Qualitatively?

To test rice bran oil quality, MEDIOCON INC likely uses standard analytical methods (like GC/HPLC) for key indicators such as Free Fatty Acids (FFA), Peroxide Value, Oryzanol, Phytosterols, Color, Moisture, and FFA levels, often checking against Indian Standards (BIS) for edible oils, ensuring stabilization (preventing rancidity) and low impurities, especially Glycidyl Esters (GEs) and Monochloropropanediol Esters (MCPDEs). The qualitative tests confirm purity, nutritional value, and safety, ensuring it meets grade-one edible oil standards. 

Key Quality Parameters & Testing Methods:

1.    Oryzanol & Phytosterols Content:

·       Test: High-Performance Liquid Chromatography (HPLC) is used to quantify these beneficial antioxidants, a key selling point for rice bran oil.

·       Goal: High levels indicate nutritional richness.

2.    Free Fatty Acids (FFA) & Peroxide Value (PV):

·       Test: Titration methods (like KOH titration for FFA) and iodometric titration for PV determine rancidity and freshness.

·       Goal: Low FFA and PV levels (e.g., << 0.10 mg KOH/g for FFA) signify fresh, stable oil.

3.    Moisture Content:

·       Test: Karl Fischer titration or gravimetric methods.

·       Goal: Low moisture prevents microbial growth and spoilage (around 12% or less is ideal).

4.    Color:

·       Test: Spectrophotometry (Lovibond or Gardner scale).

·       Goal: Light, clear color indicates effective refining.

5.    Impurities (GEs, MCPDEs, Metals):

·       Test: Gas Chromatography (GC) for GEs/MCPDEs; Atomic Absorption Spectroscopy (AAS) for metals (Iron, Copper).

·       Goal: Undetectable levels of GEs/MCPDEs and low prooxidant metals are crucial for health.

6.    Stabilization:

·       Process: Solvent extraction followed by physical refining ensures oryzanol retention and stabilizes the oil, preventing rapid degradation. 

·       Which tests are performed on Rice bran oil.Oil  Manufactured by  MEDIOCON INC ?

Tests on rice bran oil check purity, safety, and nutritional value, including Peroxide Value, Acid Value (FFA), Saponification Value, Fatty Acid Profile, Oryzanol content, and contaminants like heavy metals/pesticides, adhering to standards like FSSAI/BIS, though specific tests for Mediocon Inc. aren't listed, they'd follow these general industry practices for quality assurance. 

Common Tests for Rice Bran Oil
These tests ensure the oil is fit for consumption and meets quality standards:

·       Purity & Adulteration:

o   Saponification Value: Checks for other fats/oils; must be within 180-195 for rice bran oil.

o   Argemone Oil Test: Ensures absence of this harmful adulterant.

·       Quality & Freshness:

o   Acid Value (FFA - Free Fatty Acids): Indicates oil rancidity; should be low (below 1).

o   Peroxide Value: Measures initial oxidation.

o   Color, Odor, Taste (Organoleptic): Basic quality checks.

·       Nutritional & Health Benefits:

o   Oryzanol Content: Key antioxidant in rice bran oil.

o   Fatty Acid Profile: Determines composition (e.g., Oleic, Linoleic acids).

o   Vitamins: Testing for fat-soluble vitamins like A, D, E.

·       Safety & Contaminants:

o   Heavy Metals: Lead, Mercury, Arsenic, Cadmium.

o   Pesticide Residues: Detects harmful chemical residues.

o   Microbiological Contamination: Checks for microbes.

·       Physical Properties:

o   Specific Gravity, Cloud Point: Physical characteristics. 

Mediocon Inc. Specifics
While specific tests for Mediocon Inc. aren't detailed in general searches, any reputable manufacturer of rice bran oil, like Mediocon, would perform these standard tests to guarantee their product's safety, authenticity, and compliance with Indian (FSSAI, BIS) and international food safety regulations. You would typically find these details on their product labels, quality certificates, or by contacting them directly. 

What are the challenges in manufacturing of Rice bran oil.Oil  Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing Rice Bran Oil (RBO) faces challenges like rapid rancidity due to lipase enzymes, high wax/FFA content needing complex refining (dewaxing, deacidification), potential adulteration, and ensuring oil stability for final dosage forms, which requires stabilization (like bran stabilization) and advanced purification, with MEDIOCON INC's specific "dosage forms" likely involving microencapsulation or specialized formulations to deliver nutrients/actives, adding complexity beyond standard edible oil refining. 

General Challenges in Rice Bran Oil Manufacturing:

1.    Lipase Activity & Rancidity: Rice bran contains lipase enzymes that quickly break down oil into Free Fatty Acids (FFA), causing rancidity and oil loss, requiring immediate stabilization (heat treatment/bran stabilization) after milling.

2.    High Wax Content: RBO has high waxes, leading to haziness and requiring energy-intensive dewaxing processes, adding cost and complexity.

3.    Complex Refining: High FFA, waxes, dark color, and other impurities necessitate extensive refining (neutralization, bleaching, deodorization, dewaxing), often leading to nutrient loss.

4.    Extraction Efficiency: Optimizing extraction (solvent, temperature, flow rate) is crucial to maximize yield while minimizing degradation.

5.    Adulteration Risks: Ensuring purity and preventing blending with inferior oils is a significant concern for quality and consumer trust. 

Challenges for MEDIOCON INC's Dosage Forms:

For "dosage forms," MEDIOCON INC likely focuses on nutraceuticals or specialized products (e.g., microencapsulated RBO for controlled release, fortified oils). This adds further layers of difficulty: 

1.    Stabilization for Formulation: Standard refining stabilizes oil for cooking; dosage forms need even greater stability for long shelf-life and specific delivery, potentially needing advanced stabilization.

2.    Microencapsulation/Delivery Systems: Creating stable microcapsules or emulsions for oral delivery (capsules, liquids) is technically challenging, requiring specific polymers and processes to protect nutrients and ensure bioavailability.

3.    Bioavailability & Efficacy: Ensuring that beneficial compounds (like oryzanol, tocopherols) remain effective and are properly absorbed from the final dosage form is critical.

4.    Regulatory Compliance: Meeting strict standards for pharmaceutical/nutraceutical dosage forms (GMP, purity, dosage accuracy) is more demanding than for bulk edible oil.

5.    Scale-up of Specialized Processes: Moving from lab-scale formulation development to large-scale, consistent production of complex dosage forms is a significant hurdle. 

What is the Packing for Rice bran oil.Oil  Manufactured by MEDIOCON INC?

MEDIOCON INC's Rice Bran Oil packaging typically uses food-grade materials like tin or opaque plastic (HDPE/PET bottles) for sizes like 1-liter, ensuring light and air protection, with labels detailing batch, manufacture date, MRP, and brand info, following general food safety standards for quality rice bran oil. 

Standard Packaging Details:

·       Container Type: Look for sealed, food-grade containers, often HDPE (high-density polyethylene) bottles, PET bottles, or tins, to prevent light and air degradation.

·       Common Sizes: Expect common sizes like 1-liter bottles, with variations available.

·       Label Information: Labels must include the product name, net volume, manufacturer's name/trademark, batch number, manufacturing month/year, "Best Before" date, MRP, and customer care details. 

Key Considerations for Rice Bran Oil Packaging:

·       Light Protection: Avoid clear containers; dark glass, metal, or opaque plastics are preferred.

·       Airtight Seal: A tight seal minimizes air exposure, slowing down oxidation.

·       Quality Assurance: The packaging material should not affect the oil's properties or shelf life. 

To find the exact packaging for MEDIOCON INC, you might need to check their official website, product listings on e-commerce sites (like Ubuy India for similar products), or look for their products in retail stores, as packaging can vary slightly by region and product line. 

What should the label claim for Rice bran oil.Oil  Manufactured by MEDIOCON INC   Include?

For Rice Bran Oil by MEDIOCON INC, the label should include the product name, manufacturer details, net weight, batch info, nutritional facts (especially fatty acids like Oleic, Linoleic, Palmitic), key components like Gamma Oryzanol & Vitamin E, processing details (Refined, Bleached, Deodorized - RBD), and health claims (heart health, cholesterol reduction), adhering to FSSAI/local food regulations for ingredients, allergens, and usage instructions. 

Here's a breakdown of essential claims for the label:

1. Core Product & Manufacturer Info (Mandatory)

·       Product Name: "Rice Bran Oil" or "Refined Rice Bran Oil".

·       Manufacturer: "Manufactured by: MEDIOCON INC".

·       Address/Contact: Full business address and contact details for MEDIOCON INC.

·       Net Quantity: Weight/Volume (e.g., 1 Litre, 500 ml).

·       Batch No., Mfg. Date, Exp. Date/Best Before Date.

·       FSSAI License Number (if applicable in India). 

2. Key Ingredients & Nutritional Highlights

·       Ingredients: 100% Rice Bran Oil (Oryza Sativa Bran Oil).

·       Fatty Acid Profile (Crucial): Mention high levels of MUFAs & PUFAs, with percentages for Oleic Acid (approx. 42%), Linoleic Acid (approx. 28%), and Palmitic Acid (approx. 22%).

·       Bioactive Compounds: Highlight Gamma Oryzanol (natural antioxidant) and Vitamin E (Tocopherol). 

3. Health & Quality Claims (Based on Properties)

·       "Contains Gamma Oryzanol & Vitamin E".

·       "Helps Reduce Cholesterol".

·       "Keeps Heart Healthy".

·       "Rich in Antioxidants".

·       "Physically Refined" (if applicable).

·       "Balanced Fatty Acid Profile". 

4. Usage & Storage

·       "Ideal for All Indian Cooking" or "Suitable for Deep Frying & General Cooking."

·       "Store in a cool, dry place, away from direct sunlight."

5. Regulatory Compliance

·       Ensure the oil meets quality standards (like Iodine Value 90-105 for Rice Bran Oil).

·       Mention it's suitable for the health-conscious. 

Example Label Snippet:

MEDIOCON'S Premium Rice Bran Oil
Pure & Healthy Cooking Oil

Net Quantity: 1 Litre

Key Features:

·       Rich in Gamma Oryzanol & Vitamin E.

·       Heart Healthy & Cholesterol Reducing.

·       Balanced Fatty Acids (MUFA/PUFA).

·       Physically Refined. 

Ingredients: 100% Rice Bran Oil (Oryza Sativa Bran Oil). 

Where can Rice bran oil. Manufactured by MEDIOCON INC are procured?

Rice bran oil.Oil  Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Rice bran oil.Oil  Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Rice bran oil.Oil  Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Rice bran oil.Oil  Manufactured by MEDIOCON INC product, regardless of the procurement source.