Rosemary oil 8000-25-7 Oil Manufactured by MEDIOCON INC

 

 

 

Rosemary oil Oil Manufactured by MEDIOCON INC

 Name: Rosemary oil Oil

CAS No :8000-25-7

Molecular Weight :Not applicable

Molecular formula:  

Not applicable (It is a natural essential oil mixture containing 1,8-cineole, camphor,

αalpha

𝛼

·       -pinene, etc

·       Synonyms: Rosmarinus officinalis oil, Rosemary Essential Oil, Rosemary Leaf Oil, Oleum Rosamarinii

·       Appearance: Colorless to pale yellow or greenish-yellow liquid

·        Solubility :   Insoluble in water; soluble in alcohol (ethanol) and organic solvents (e.g., oils)

·        

Use :

·        

o   Hair & Skin Care: Promotes hair growth, treats dandruff, and acts as a skin-conditioning agent

o   Aromatherapy: Used to reduce stress, improve concentration, and boost memory

o   Industrial/Flavor: Used in fragrances, soaps, detergents, cosmetics, and food seasoning (sauces, meats)

o   Medicinal: Used for pain relief (arthritis), respiratory issues, and acting as a stimulant 

·       ROSEMARY OIL | CAS Number : 8000-25-7 - Avanscure

Table_content: header: | Quantity | Unit | Price ( $ ) | Net Amount | row: | Quantity: 00 | Unit: mg | Price ( $ ): 00 | Net Amoun...

 

Avanscure

·       Rosemary, ext. - Registration Dossier - ECHA

3, according to CLP criteria). Rosemary oil is a clear, colourless to pale yellow or greenish yellow liquid, mobile, with a balsam...

 

ECHA

·       Rosemary Essential Oil: Benefits, Uses & Insights - Aroma Web

Rosemary Essential Oil * Salvia rosmarinus. (Synonym: Rosmarinus officinalis) Rosemary Essential Oil Profile Table of Contents: In...

 

 How is  Rosemary oil Oil  manufactured by MEDIOCON INC Synthesized?

 

MEDIOCON INC likely manufactures its rosemary oil using standard industry methods like steam distillation, where steam passes through rosemary plant material to vaporize the essential oils, which are then condensed and collected; or potentially supercritical CO2 extraction for a purer extract, often sourced directly from farmers, then processed in-house for quality control, following GMP/FDA standards, rather than "synthesizing" it, as essential oils are natural extracts. 

General Manufacturing Process for Rosemary Essential Oil (Likely Used by MEDIOCON INC) 

1.    Sourcing & Preparation: Fresh or dried rosemary (Rosmarinus officinalis) is sourced, often directly from farms, as described by suppliers like Aadhunik Ayurveda.

2.    Steam Distillation: Plant material is placed in a distiller, and steam is forced through it, carrying the volatile oil components.

3.    Condensation & Separation: The steam and oil mixture is cooled, condensing into water and oil, which are then separated.

4.    Extraction Methods: Other methods include:

1. Hydrodistillation: Boiling plant material in water.
2. Supercritical CO2 Extraction: Using carbon dioxide under pressure to extract oils, offering high purity.

5.    Post-Processing (Optional): Filtration, drying, and sometimes standardization with carriers (like sunflower oil) for specific applications.

6.    Quality Control: Companies like MEDIOCON INC, if ISO/GMP/FDA certified, ensure high purity through in-house processing and adherence to standards. 

Key Takeaway: Rosemary oil isn't truly "synthesized" (chemically created); it's extracted from the plant, with steam distillation being the most common method to obtain the pure essential oil. 

What are the different  dosage forms  of   Rosemary oil Oil  Manufactured  by  MEDIOCON INC?

Based on the provided search results, the rosemary oil products labeled under "MEDIOCON INC" (specifically via DailyMed for Rosemary Essential Oil and related hair/scalp products) are manufactured in the following liquid dosage forms and packaging sizes: 

Dosage Forms

·       Liquid (Essential Oil): Marketed for topical application, hair, and scalp care.

·       Liquid (100% Pure/Grade): Marketed for topical use. 

Packaging Sizes (Bottle Types) 

·       5 mL in 1 BOTTLE

·       15 mL in 1 BOTTLE

·       30 mL in 1 BOTTLE

·       50 mL in 1 BOTTLE

·       100 mL in 1 BOTTLE 

 How Rosemary oil Oil  Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Based on common manufacturing processes for high-quality,, plant-derived oils, Rosemary oil is typically produced through

steam distillation or supercritical

2

extraction, which ensures the purity of the active compounds like 1,8-cineole and camphor. 

The dosage forms, particularly for topical or hair growth applications, are Prepared by blending the concentrated oil with carrier oils or gelling agents to enhance stability and penetration. 

1. Manufacturing Process of Rosemary Oil 

• Harvesting & Preparation: Fresh flowering tops and leaves of Rosmarinus officinalis are collected, dried slightly, and sometimes crushed to prepare for extraction.
• Steam Distillation (Common Method): The rosemary material is placed in a distillation still. Steam is passed through the material, vaporizing the essential oil. The mixture is condensed back into liquid, and the oil separates from the water, allowing it to be collected.
• Supercritical

2

Extraction (Advanced Method): This method uses

2

at high pressure to extract volatile compounds, allowing for a better preservation of the chemical profile without using harmful solvents.

• Filtration & Storage: The extracted oil is filtered to remove impurities and stored in dark glass bottles to prevent oxidation. 

2. Preparation of Dosage Forms 

The pure, concentrated oil is typically converted into consumer-ready dosage forms through these methods: 

• Diluted Hair/Scalp Oil (Topical Application):
• Preparation: Pure rosemary oil is diluted with carrier oils such as jojoba or coconut oil.
• Dosage: Generally, a few drops (approx. 1 mL) are used, often applied to the scalp for hair growth, typically twice daily.
•  

 What are the appropriate Dosage forms of Rosemary oil Oil  Manufactured  by  MEDIOCON   INC?                

Based on the provided search results, there is no direct evidence identifying a manufacturer named "MEDIOCON INC" that produces rosemary oil. 

However, based on standard pharmaceutical and consumer product labels, rosemary oil is typically available in liquid, essential oil form.

Typical Packaging and Application:

·       Packaging Sizes: Rosemary essential oil is commonly packaged in various bottle sizes, such as 5 mL, 15 mL, 30 mL, and 50 mL.

·       Application: It is primarily intended for topical application, particularly for the hair and scalp, and is often dispensed using a dropper. 

General Methods of Use:

·       Topical Application: When applied topically, especially to the scalp, rosemary oil is typically massaged into the skin. It is often recommended for use on areas where support is desired.

·       Dilution: Due to its potency, rosemary oil is frequently diluted with a carrier oil, such as coconut or jojoba oil, before applying to the skin or scalp.

·       Application Duration: After application, it can be left on for a period of time, ranging from several hours to overnight. 

Important Precautions:

·       External Use Only: Rosemary oil is intended for external application and should not be ingested.

·       Skin Sensitivity: Performing a patch test on a small area of skin before widespread use is advisable to check for any irritation.

·       Specific Health Considerations: Individuals with certain health conditions, such as epilepsy or high blood pressure, or who are pregnant, may need to avoid using pure rosemary oil. 

When should Rosemary oil Oil  Manufactured by MEDIOCON INC be taken?

Based on general product information for rosemary oil and specific instructions for hair loss treatments, rosemary oil (including potential products manufactured by MEDIOCON INC) is intended for topical use (skin and scalp) and aromatherapy, not for internal consumption. 

For potential benefits related to hair, rosemary oil is typically used topically. General guidelines for its use on the scalp often involve diluting it with a carrier oil to help prevent irritation. 

Common approaches for applying rosemary oil topically may include:

·       Dilution: Mixing a small amount of rosemary oil with a carrier oil like coconut or jojoba oil is often recommended.

·       Application Timing: While it can be applied at different times, some sources suggest application at night, allowing it to remain on the scalp overnight before washing the hair in the morning.

·       Duration on Scalp: The diluted oil is typically left on the scalp for a period of time, such as at least 30 minutes, before washing. Leaving it on for a longer duration, such as overnight, is also a common practice.

·       Frequency of Use: Regular use is often suggested, with recommendations varying from a few times per week to daily application, depending on individual tolerance.

·       Consistency: Achieving noticeable results with rosemary oil for hair often requires consistent use over several months. 

Important Precautions:

·       Applying undiluted essential oils directly to the skin or scalp is not recommended due to the potential for irritation.

·       Performing a patch test on a small area of skin before applying it more widely is advisable to check for sensitivity.

·       Care should be taken to avoid contact with the eyes. 

 What are the effects And Side effects of Rosemary oil Oil  Manufactured by MEDIOCON INC?

Based on general findings regarding Rosemary Essential Oil (often marketed with similar properties, though specific manufacturer data for MEDIOCON INC may vary), this product is primarily used topically for hair growth and scalp health. 

Here are the general effects and potential side effects of rosemary oil:

Effects and Benefits

·       Hair Growth Promotion: Rosemary oil is known to stimulate hair follicles, with studies suggesting it may be as effective as 2% minoxidil in increasing hair count, making it a popular choice for treating alopecia and androgenetic hair loss.

·       Improved Scalp Health: It possesses antimicrobial properties that can help reduce dandruff and soothe itchy, dry scalps.

·       Increased Circulation: When massaged into the scalp, it acts as a circulatory stimulant, increasing blood flow, which helps deliver oxygen and nutrients to hair roots.

·       Anti-inflammatory & Antioxidant Properties: It contains compounds like carnosic acid, which help combat oxidative stress and soothe inflammation. 

Potential Side Effects

·       Skin Irritation: Directly applying concentrated (undiluted) rosemary oil can cause redness, itching, or a burning sensation on the skin, particularly for those with sensitive skin.

·       Increased Hair Shedding (Initial): Some users may experience an initial increase in hair shedding as circulation improves and weak hair is replaced by new, stronger hair. This is usually temporary.

·       Allergic Reactions: As with any essential oil, some individuals may experience allergic contact dermatitis.

·       Respiratory Irritation: Inhaling concentrated vapor may cause breathing issues or coughing, especially in people with asthma. 

  How is Rosemary oil Oil  Manufactured by MEDIOCON  INC  Tested Qualitatively?

Mediocon Inc. likely tests their Rosemary oil Oil qualitatively using advanced analytical techniques like Gas Chromatography-Mass Spectrometry (GC-MS) to identify key chemical components (terpenes, ethers) and ensure purity, alongside physical tests (smell, appearance, viscosity) and potential biological assays (antimicrobial activity), ensuring consistency and adherence to industry standards for their pharma, food, and fragrance clients. 

Key Qualitative Testing Methods

1.    Gas Chromatography-Mass Spectrometry (GC-MS):

·       Purpose: This is the gold standard for identifying the unique chemical fingerprint of essential oils, revealing the types and amounts of compounds like α-pinene, limonene, and caryophyllene.

·       How it works: The oil is vaporized and separated (GC), then fragmented and identified by mass (MS).

2.    Physical & Organoleptic Tests:

·       Appearance & Odor: Checks for clarity, color, and the characteristic woody, spicy aroma, ensuring it matches the expected profile.

·       Refractive Index & Specific Gravity: Measures physical properties for consistency.

3.    Microbiological & Biological Assays (Potentially):

·       Antimicrobial Testing: Methods like well diffusion or broth microdilution test effectiveness against bacteria or fungi, indicating oil potency.

·       Cell-based Assays: For research, testing effects on cancer cells (like MDA-MB-231) using MTT assays, though this is more R&D.

4.    Purity & Adulteration Checks:

·       GC-MS & Isotope Ratio Mass Spectrometry: Detects adulterants or synthetic additives, a critical factor for quality. 

·       Which tests are performed on Rosemary oil Oil  Manufactured by  MEDIOCON INC ?

Based on the product portfolio of Mediocon Inc, a manufacturer, wholesaler, and supplier of natural products including essential oils, their rosemary oil (CAS Number: 8000-25-7) is typically subject to rigorous quality control measures. 

While specific batch-level Certificates of Analysis (COA) are generated at the time of manufacturing, the standard tests performed on Rosemary Oil (Rosmarinus officinalis) to ensure purity and quality generally include: 

·       Gas Chromatography-Mass Spectrometry (GC-MS): This is the primary test to determine the chemical composition, identifying the major constituents and confirming the purity.

·       Physical Parameter Testing:

o   Appearance/Color: Confirmed to be colorless or pale yellow.

o   Refractive Index: Tested for optical clarity and purity.

o   Relative Density (Specific Gravity): Typically checked to be around 0.908 g/mL at 25 °C.

o   Optical Rotation: Measures the rotation of polarized light.

·       Chemical Tests:

o   Acid Value: Verified to be lower than 1.0, ensuring the oil is not rancid or acidic.

o   Peroxide Value: To detect oxidation levels.

·       Solubility Test: Verified as insoluble in water. 

Key Quality Assurances for Mediocon Inc Products:

·       Manufacturing Standards: Products are produced in GMP (Good Manufacturing Practices) and ISO certified facilities.

·       Product Profile: The oil is tested to confirm it is 100% pure & natural, free from mineral oil, parabens, and silicones. 

For specific, up-to-the-minute testing parameters for a particular batch, a, Certificate of Analysis (COA) should be requested directly from Mediocon Inc.

What are the challenges in manufacturing of Rosemary oil Oil  Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing rosemary oil dosage forms faces challenges in extraction consistency (yield, quality), stability (oxidation, degradation of active compounds like carnosic acid), formulation (solubility, encapsulation efficiency for water-insoluble oil), and ensuring safety/standardization (solvent residues, concentration levels for internal use). For a specific company like MEDIOCON INC., challenges would involve selecting optimal extraction (e.g., supercritical CO2 vs. steam distillation), controlling particle size, preventing degradation during processing, and creating stable, effective delivery systems (emulsions, encapsulations). 

Key Challenges in Rosemary Oil Manufacturing:

1.    Extraction & Yield Optimization:

·       Method Selection: Choosing between steam distillation (simpler, potential degradation) and supercritical CO2 (high quality, expensive equipment).

·       Parameter Control: Optimizing temperature, pressure, and particle size for maximum yield and desired chemical profile.

·       Solvent Concerns: Minimizing residues from organic solvents like hexane if used.

2.    Stability & Degradation:

·       Oxidation: Rosemary oil's volatile compounds are prone to oxidation, affecting potency and shelf life.

·       Thermolabile Compounds: High heat during extraction or processing can degrade beneficial components like carnosic acid.

3.    Formulation & Delivery:

·       Solubility: Rosemary oil is hydrophobic, making it hard to incorporate into aqueous (water-based) systems.

·       Encapsulation: Achieving high encapsulation yield and efficiency (e.g., with maltodextrin, gum arabic) for stable delivery in powder or emulsion forms.

·       Emulsions: Maintaining long-term stability and preventing phase separation in oil-in-water emulsions.

4.    Standardization & Purity:

·       Active Compounds: Ensuring consistent levels of key compounds (carnosic acid, rosmarinic acid, flavonoids) across batches.

·       Purity: Removing impurities, potential toxins, or solvent residues, especially for internal use.

5.    Dosage Form Specifics (e.g., Chewables, Sprays):

·       Taste & Odor: Masking the strong, bitter taste and pungent odor for consumer acceptance in oral forms.

·       Release Profile: Controlling the release rate for desired therapeutic effects (e.g., quick action for dyspepsia).

·       Regulatory Compliance: Meeting strict standards for food/pharmaceutical use (e.g., GRAS status for extracts). 

For MEDIOCON INC., addressing these points means balancing cost, efficiency, product quality, and consumer safety in their rosemary oil products, potentially using advanced techniques like supercritical extraction and encapsulation. 

·       Poor water solubility limits absorption, requiring advanced formulation (e.g., nanoemulsions) for better delivery, notes Frontiers in Pharmacology.

. 

What is the Packing for Rosemary oil Oil  Manufactured by MEDIOCON INC?

MEDIOCON INC's rosemary oil packaging, according to FDA drug label information, comes as 5 mL in a box (Type 0, not a combination product), using an NDC code 84525-316-01, suggesting it's marketed for medicinal or specific therapeutic purposes rather than just general aromatherapy, with standard small vials or bottles in a box being common for such items. 

Key Details:

·       Volume: 5 mL.

·       Container: In a box.

·       Type: Not a combination product (indicating it's pure or a single-ingredient formulation). 

While other manufacturers offer rosemary oil in various drums, HDPE, or larger glass bottles, MEDIOCON's specific packaging listed is for small, precise doses, likely for targeted treatment. 

What should the label claim for Rosemary oil Oil  Manufactured by MEDIOCON INC   Include?

For Rosemary oil Oil from MEDIOCON INC, label claims should focus on purity, source, processing (cold-pressed), benefits (aroma, cleaning, potential therapeutic uses), storage, and certifications (organic, non-GMO), adhering to regulatory guidelines (like FDA, USDA) for essential oils, highlighting natural essence, potentially listing key components like limonene, and clearly stating usage instructions, ensuring it reflects the oil's quality and intended use, whether cosmetic or culinary. 

Here's a breakdown of key elements to include:

Mandatory Information:

1.    Product Name: Rosemary oil Oil (or Cold-Pressed Lemon Essential Oil).

2.    Brand Name: MEDIOCON INC.

3.    Net Quantity: (e.g., 15mL, 30mL).

4.    Ingredients: 100% Pure Rosemary oil Oil (or Lemon Peel Oil).

5.    Manufacturer Details: MEDIOCON INC, address, contact info.

6.    Batch/Lot Number & Expiry/Best Before Date.

7.    Storage Instructions: Store in a cool, dark place, tightly sealed, away from heat.

8.    Warning/Caution: For external use only (if cosmetic); keep out of reach of children; avoid contact with eyes; dilute with carrier oil. 

Recommended Claims & Details:

·       Source/Process: "Extracted from fresh Lemon Peels," "Cold-Pressed for Purity".

·       Purity: "100% Pure & Natural," "Therapeutic Grade" (if applicable).

·       Aroma/Scent: "Uplifting Citrus Aroma," "Fresh Lemon Scent".

·       Benefits (Use cautiously & back with science): "Promotes Cleanliness," "Refreshing," "Natural Fragrance," "Aids in aromatherapy".

·       Key Component: May list "Contains Limonene".

·       Certifications: USDA Organic, Non-GMO, Vegan (if applicable).

·       Usage Suggestions: "For diffusers," "For DIY cleaning solutions," "Add to soaps/lotions". 

Where can Rosemary oil Oil  Manufactured by MEDIOCON INC are procured?

Rosemary oil Oil  Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find Rosemary oil Oil  Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for Rosemary oil Oil  Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the Rosemary oil Oil  Manufactured by MEDIOCON INC product, regardless of the procurement source.