SEPTECH ST60-C18,10 MICRON 7631-86-9 Manufacture ,supplier, exporter by Mediocon INC

 

 

 

 

 SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC

 

 Name: SEPTECH ST60-C18,10 MICRON

CAS No:   7631-86-9

Molecular Weight:  174.17 g/mol

Molecular formula:  CaC₄H₄O₄.H₂O

o   Synonyms: C18 (shorthand for the bonded phase)

o   ODS (Octadecylsilane)

o   RP18 (Reversed Phase 18)

o   Octadecyl-bonded silica

o    

o   Appearance: As a bulk material (packing media), it is generally a fine, white powder or granular solid.

o   When packed inside an HPLC column, it is a solid component of the analytical instrument.

 Solubility : The material itself is an insoluble solid used in liquid chromatography. The solubility of analytes (substances being analyzed) in various solvents is a key principle of its use, but the packing material does not dissolve in the typical mobile phases used (e.g., water, methanol, acetonitrile mixtures)..

Use :

It is used in High Performance Liquid Chromatography (HPLC) and preparative chromatography. It functions as a reversed-phase stationary phase, optimized for the separation, purification, and analysis of non-polar and moderately polar small molecules and biomolecules.

Benefits of SEPTECH ST60-C18,10 MICRON include [1][2][3]:

- PH Regulation: Helps maintain pH balance in products

- Antimicrobial Properties: Inhibits microbial growth

- Moisturizing: Attracts and retains moisture in skin and products

Consult relevant guidelines and regulations for specific use cases.

 

 How is  SEPTECH ST60-C18,10 MICRON manufactured by MEDIOCON INC Synthesized?

·  Start with Porous Silica Particles

·       Spherical silica with controlled size and pore structure is synthesized (typically through sol-gel processing of silicon alkoxides such as tetraethyl orthosilicate under controlled conditions).

·       The particles are washed and activated to present silanol (Si–OH) groups on the surface.

·  Chemical Bonding of Octadecyl Ligands (C18)

·       The silica surface is reacted with an organosilane reagent such as chlorodimethyl octadecylsilane or octadecyltriethoxysilane.

·       These silanes undergo silanization, forming covalent Si–O–Si–C18 linkages to the surface silanols.

·       This grafts long C18 hydrocarbon chains onto the surface, creating the hydrophobic stationary phase. materialharvest.com

·  End-Capping (Optional But Common)

·       Unreacted silanol groups on the silica are often reacted with a smaller silane (e.g., trimethylchlorosilane) to “end-cap” residual OH groups.

·       End-capping reduces unwanted polar interactions and improves chromatographic performance. analiticaweb.it

·  Purification and Quality Control

·       The functionalized silica is washed to remove unreacted reagents and by-products, dried, and sieved.

·       Quality checks ensure uniform carbon load, ligand density, particle size distribution, and batch reproducibility.

What are the different  dosage forms  of   SEPTECH ST60-C18,10 MICRON Manufactured  by  MEDIOCON INC?

. Bulk Media (Loose Packing Material)

·       1 kg loose pack of SepTech ST60-C18 (10 µm) — for repacking columns or preparative use. chem-agilent.com

·       100 g loose bulk pack — smaller research quantities. chem-agilent.com

·       10 kg bulk pack — larger preparative or industrial orders. chem-agilent.com

·       25 kg bulk pack — very large preparative/extraction batch processing. chem-agilent.com

2. Ready-to-Use HPLC Column Formats
These are pre-packed analytical/preparative HPLC columns that use SepTech ST60-C18, 10 µm packing:

·       SepTech ST60-C18, 10 µm 30 × 4.6 mm conventional HPLC column — analytical column form factor (pre-packed). MZ-Analysentechnik
(Other packed column dimensions may be offered by some suppliers, but this is a commonly listed ready column format for this media.)

 How SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Sterile dosage form can be defined as a dosage form that is free from microorganisms, intended for administration by injection, infusion, or implantation into the human or animal body. 

·       Examples include injections, saline solutions, and eye drops. 

·       Parenteral dosage forms are administered via routes other than the oral route, which is derived from the Greek words "para" and "enteron" meaning 'to avoid the intestine'. 

·       These products must meet specific requirements such as sterility, being pyrogen-free, and free of particulate matter. 

·       The manufacturing process is highly regulated and requires specialized equipment and protocols to bypass the body's usual defenses against infection. 

What are the appropriate Dosage forms of SEPTECH ST60-C18,10 MICRON Manufactured  by  MEDIOCON   INC?                

SEPTECH ST60-C18,10 MICRON is available in various dosage forms, including [1][2]:

- Oral Tablets: For supplementation or therapeutic use

- Capsules: For oral administration

- Powder: For use in food products, cosmetics, or pharmaceuticals

- Granules: For food products or pharmaceutical applications

The choice of dosage form depends on the intended use, industry, and desired release profile.

When should SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC be taken?

SEPTECH ST60-C18, 10 MICRON (by Mediocon Inc / SepTech) is not a medicine or dietary supplement — it’s a chemical/analytical chromatography media used in laboratories. Specifically, it’s a type of C18 reversed-phase packing material (silica particles coated with long hydrocarbon chains) commonly used for HPLC (High-Performance Liquid Chromatography) or solid-phase extraction (SPE) separations in chemical analysis and purification workflows. Agilent Technologies

📌 What it is

• Chemical/analytical product, not for human consumption.
• Used as a stationary phase for separating or purifying organic molecules in lab equipment.
• “10 micron” refers to the particle size of the sorbent material.
• “C18” refers to the octadecyl chain chemistry suitable for reversed-phase chromatography. Agilent Technologies

🧪 When/how it is used

This material is used in laboratory equipment by trained personnel in contexts such as:

• Packing into chromatography columns for HPLC separations.
• As part of solid-phase extraction cartridges to purify or concentrate samples before analysis.
• In research, quality control, environmental testing, pharmaceuticals, food science, etc.

There is no “when to take it” in the sense of dosage or consumption — it’s never taken internally or used as a drug. Instead:

 What are the effects And Side effects of SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC?

·       SepTech: A brand name for separation products, often chromatography media.

·       ST60-C18: Indicates a silica-based stationary phase (like Octadecyl silane, C18) used in High-Performance Liquid Chromatography (HPLC) for separating organic molecules.

·       10 Micron: The particle size of the packing material, affecting separation efficiency.

·       Mediocon Inc.: The supplier or manufacturer. 

Effects (in a lab/analytical context):

·       Separation: Its primary "effect" is to separate complex mixtures into individual components based on their chemical properties (retention).

·       Purification: Used in purification processes for various substances. 

  How is SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON  INC  Tested Qualitatively?

SEPTECH ST60-C18, 10 micron (manufactured/distributed by Mediocon Inc) is a reversed-phase silica stationary phase packing material used in prep-HPLC/flash chromatography — not a pharmaceutical drug. Because of that, “qualitative testing” refers to quality control and characterization of the stationary phase material and its chromatographic performance, not dosage or clinical evaluation.

While specific quality documentation for Mediocon’s lot tests isn’t published online, standard qualitative tests for C18 bonded silica media like SEPTECH ST60-C18 generally include the following categories used across chromatography media manufacturers

   Which tests are performed on SEPTECH ST60-C18,10 MICRON Manufactured by  MEDIOCON INC ?

These confirm the physical properties and chemistry of the bulk packing material:

• Particle Size and Distribution

·       Verify the 10 µm nominal size and uniform distribution using particle sizing methods (e.g., laser diffraction).

·       Ensures consistent column packing and reproducible flow. analiticaweb.it

• Pore Size and Surface Area

·       Measure pore diameter (~60 Å) and internal surface area (BET analysis).

·       Influences capacity and kinetics of separations. analiticaweb.it

• Chemical Composition & Bonding

·       Confirmation of C18 (octadecyl) ligand presence and coverage density.

·       Detection of silica purity and residual silanol content (impact on selectivity). analiticaweb.it

• Carbon Load & Ligand Density

·       Evaluates how much C18 is bonded and the efficiency of bonding.

·       Higher carbon load improves hydrophobic retention.

What are the challenges in Manufacturing of Banana Extract Manufactured by MEDIOCON   INC API?

1.    Raw Material Variability: Bananas vary greatly in chemical composition (bioactives, water content) due to variety, growing conditions, and ripeness, making consistent starting material difficult.

2.    Extraction Method Optimization: Choosing and optimizing methods (like Microwave-Assisted Extraction - MAE, solvent extraction) to efficiently extract desired compounds (phenols, vitamins) without degrading them is complex, requiring specific power, time, and solvent ratios.

3.    Scale-Up Issues: Processes that work in a lab may not translate well to industrial scale, leading to unexpected impurities or lower yields, requiring intensive R&D monitoring.

4.    Purity & Impurity Profiling: Isolating the target API from other plant compounds and ensuring it's free from contaminants (pesticides, heavy metals) is crucial for pharmaceutical use.

5.    Stability & Shelf-Life: Banana extracts contain sensitive compounds (like Vitamin C/E) that can degrade over time, requiring careful stabilization and formulation.

6.    Regulatory Compliance: Meeting stringent global GMP (Good Manufacturing Practices) and FDA/EMA standards for an API derived from a natural source adds significant testing and documentation burden.

What are the challenges in manufacturing of SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON  INC ’s Dosage forms?

The product SEPTECH ST60-C18, 10 MICRON is a material used in high-performance liquid chromatography (HPLC) columns for purification, not a finished pharmaceutical drug product (dosage form) itself. It is used as a C18 reverse phase media with a 10 µm particle size. 

Mediocon Inc. is a supplier of pharmaceutical chemicals, APIs, and intermediates. They supply this material to companies who then use it in their manufacturing or purification processes. 

Therefore, the manufacturing challenges relate to its use as a purification medium in general pharmaceutical manufacturing, particularly for the purification of small molecules, rather than the challenges of a specific dosage form. 

Key manufacturing challenges associated with using or producing compounds involving this type of material and particle size include:

What is the Packing for SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC?

The SEPTECH ST60-C18, 10 MICRON, manufactured by SepTech (part of Mediocon Inc. or related to Avantor/VWR), is a preparative chromatography packing material sold in bulk quantities like 100g, 1kg, and 25kg bags, designed for large-scale separation, typically for HPLC columns or bulk filling, with C18 (Octadecyl) chemistry on a 10µm silica base for reversed-phase applications. 

Key Packing Details:

·       Product Type: Preparative Chromatography Packing Material (Bulk).

·       Chemistry: C18 (Octadecyl, RP-18).

·       Particle Size: 10 µm.

·       Base Material: Silica.

·       Common Pack Sizes: 100g, 1kg, 25kg

What is shelf life Of SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC? 

SEPTECH ST60-C18,10 MICRON typically has a shelf life of 3 years when stored properly in a tightly closed container in a cool, well-ventilated area, away from incompatible substances like oxidizing agents.

What should the label claim for SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC   Include?

Product Identification

The label should clearly state:

·       Product Name:
SEPTECH ST60-C18

·       Particle Size:
10 Micron (10 µm)

·       Material Type:
C18-bonded silica (Octadecylsilane bonded silica)

·       Pore Size (if applicable):
60 Å (Angstrom)

---

2. Composition / Description

A concise qualitative description, for example:

Octadecyl (C18) chemically bonded to high-purity porous silica gel.

This serves as the identity claim rather than a quantitative “strength” claim.

Where can SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC are procured?

SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the SEPTECH ST60-C18,10 MICRON Manufactured by MEDIOCON INC product, regardless of the procurement source.