ZIRCONYL CHLORIDE OCTAHYDRATE, Manufacturer, exporter ,supplier ,by MEDIOCON INC

 

 

 

ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC

 

   Name : ZIRCONYL CHLORIDE OCTAHYDRATE,

CAS No:   13520-92-8

Molecular Weight:  322.25 g/mol

Molecular formula:  ZrOCl₂ · 8H₂O or Cl₂H₁₆O₉Zr

·       Synonyms: Zirconium oxychloride octahydrate

·       Zirconium(IV) oxide chloride

·       Basic zirconium chloride

·       Dichloro   oxozirconium

·       Zirconium dichloride oxide octahydrate 

 Appearance:  White powder, solid, or tetragonal crystals

 Solubility :  Very soluble in water and ethanol.

Use :

Zirconyl chloride octahydrate is a versatile chemical intermediate used in various applications: 

·       As a precursor for preparing other zirconium compounds, including zirconium oxide for advanced ceramics and refractory materials.

·       In the synthesis of mixed zirconium phosphonates for use in catalysis and ion exchange.

·       As an additive in paints, plastics, and glazes where heat resistance is needed.

·       As a fiber treatment agent and a rubber additive.

·       In acid dyes and pigment toners.

·       In antiperspirant formulations. 

 

 How is  ZIRCONYL CHLORIDE OCTAHYDRATE,manufactured by MEDIOCON INC Synthesized?

1.    From Zirconium Tetrachloride (ZrCl₄):

·       Dissolve ZrCl₄ in an alcohol (e.g., methanol).

·       Filter to remove insoluble impurities.

·       Add a calculated amount of water to hydrolyze the ZrCl₄, causing ZrOCl₂·8H₂O to precipitate.

·       Separate the crystals via vacuum filtration and dry.

2.    From Zircon Sand (Hydrometallurgical Route):

·       Alkaline Fusion/Leaching: Zircon sand (ZrSiO₄) is treated with lime or alkali at high temperatures to form calcium zirconate and silicates, then leached with acid.

·       Hydrochloric Acid Treatment: Dissolving zirconium compounds in HCl to form zirconyl chloride solution.

·       Purification & Crystallization: Adding sulfuric acid, alkali, or ammonia to precipitate impurities, then dissolving the intermediate zirconium hydroxide in HCl, concentrating, and cooling to crystallize ZrOCl₂·8H₂O.

3.    Direct Precipitation (from Hydrofluoric Acid):

·       Dissolve zirconyl chloride in HCl, add phosphoric acid, and use infrared radiation to form crystals (though this may yield zirconium phosphate). 

What are the different  dosage forms  of   ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured  by  MEDIOCON INC?

Mediocon Inc. manufactures Zirconyl Chloride Octahydrate as a raw material in powder or crystalline solid form. It is primarily sold as a chemical intermediate for use in various industrial applications, not as a finished pharmaceutical product or a specific dosage form for medical use. 

The available forms are:

·       Powder

·       Crystalline solid (crystals) 

This compound is often used in the manufacture of textiles, ceramics, enamels, and catalysts. It is also available in aqueous solution from other suppliers, but the forms from the manufacturer you mentioned appear to be solid. 

 How ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC   Dosage Forms are prepared?

Zirconyl chloride octahydrate, manufactured by MEDIOCON INC as a pharmaceutical intermediate, is primarily used as a

raw material or precursor chemical in the production of other materials, rather than forming a direct dosage form itself. It is used to synthesize active pharmaceutical ingredients (APIs), catalysts, and other specialty materials. 

The specific "dosage forms" prepared using zirconyl chloride octahydrate are the final zirconium-based compounds, which can include: 

• Zirconium phosphates and phosphonates: These can be used in medicine as biomaterials for hard tissue reconstruction (e.g., in dentistry) or as ion-exchange materials, which are then formulated into their specific final applications. Zirconium phosphate granules synthesized using zirconyl chloride are used in dialysis systems to remove components like ammonia from a fluid stream.

nanoparticles or ceramics: These are used in medical fields for surgical implants due to their biocompatibility and durability.

• Antiperspirants: Zirconyl chloride is a key ingredient in the manufacture of certain antiperspirants, where the final product is formulated as a spray, roll-on, or solid stick. 

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What are the appropriate Dosage forms of ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured  by  MEDIOCON   INC?                

Zirconyl chloride octahydrate manufactured by MEDIOCON INC is supplied as a raw material in powder or crystalline solid form and does not have a specific "dosage form" in itself. It is used as an excipient or intermediate in the manufacture of other pharmaceutical products and is not a direct drug product for patient use. 

In the pharmaceutical industry, high-purity zirconyl chloride octahydrate functions primarily as an excipient in the production process, typically in: 

·       Oral dosage forms: It is used in enteric-coated capsules and tablets as a controlled-release agent, regulating the diffusion rate of active pharmaceutical ingredients (APIs) in the gastrointestinal tract.

·       Topical preparations: It is also suitable for use in certain topical (skin) applications, provided it meets specific pharmacopeial standards.

·       Medical diagnostics/laboratory use: It is an ingredient in laboratory reagents, such as zirconyl hematoxylin solution, used in histology for staining purposes. 

When should ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC be taken?

Zirconyl Chloride Octahydrate (ZrOCl₂·8H₂O) is a chemical compound, not a medicine for consumption, but used in industrial applications like ceramics, textiles, antiperspirants, and as a laboratory reagent or catalyst; therefore, it should never be "taken" internally but handled with care as a corrosive chemical in a lab or industrial setting, using personal protective equipment to avoid skin/eye contact and inhalation. 

What it is used for (Industrial/Lab, not internal consumption):

·       Manufacturing: Precursor for other zirconium compounds, ceramics, paints, textiles, and anti-perspirants.

·       Catalysis: Used as a non-toxic catalyst in solvent-free chemical reactions.

·       Reagent: For preparing zirconia thin films and other chemical processes. 

Safety & Handling (Critical):

·       Corrosive: Ingestion causes severe damage and risk of perforation (stomach/esophagus).

·       Protective Gear: Use gloves, eye protection, and avoid dust/skin contact.

·       Disposal: Follow official regulations; do not release into the environment

 What are the effects And Side effects of ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC?

Zirconyl chloride octahydrate (ZrOCl₂·8H₂O) is a corrosive inorganic chemical used mainly in research, materials synthesis, catalysis, dyes and pigments, ceramics, and similar industrial applications. It is not intended for ingestion, medical treatment, or household use. Benchchem

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⚠️ Hazards & General Effects

This chemical is considered hazardous and corrosive. It can cause severe damage on contact or exposure. ChemicalBook

1. Skin Contact

·       Causes severe irritation and burns on contact.

·       Can produce inflammation, blistering, and tissue damage. Nile Chemicals

2. Eye Contact

·       Seriously damaging — may cause severe irritation, corneal injury, or even vision impairment if not treated promptly. Benchchem

3. Respiratory Exposure

·       Inhaling dust or aerosol can irritate the nose, throat, and lungs.

·       Prolonged or heavy exposure could lead to coughing, sneezing, and difficulty breathing. Nile Chemicals

4. Ingestion

·       Harmful if swallowed; it is corrosive to the digestive tract.

·       Can cause severe pain, swelling, ulceration and dangerous internal damage.

·       Do not induce vomiting if ingestion occurs and seek medical help immediately. ChemicalBook

5. Chronic & Long-Term Effects

·       Limited specific data on long-term effects in humans.

·       Some animal studies suggest possible genetic effects and effects on internal systems, but evidence is not definitive for humans. Suvchem Laboratory Chemicals

·       Routine exposure without protection may lead to dermatitis or respiratory irritation over time. Nile Chemicals

  How is ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON  INC  Tested Qualitatively?

A reputable manufacturer like Zirconium Chemicals Pvt. Ltd. (or similar) would perform these tests:

·       Identity: Confirmed by titration and specific chemical reactions (e.g., precipitation tests with fluorides or phosphates).

·       Purity: Verified by ICP-AES for trace impurities and titration for ZrOCl₂ content.

·       Physical Characteristics: Checked for color, form, and particle morphology (SEM). 

These methods ensure the Zirconyl Chloride Octahydrate meets specific industry standards, often following guidelines from bodies like the ACS Publications (American Chemical Society) for reagent grade chemicals. 

   Which tests are performed on ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by  MEDIOCON INC ?

For MEDIOCON INC's Zirconyl Chloride Octahydrate, standard quality control tests focus on purity and composition, including Assay (Zirconium content via complexometric titration), limits for impurities like Iron, Titanium, and Sulfate, and identifying the material (e.g., using FTIR spectroscopy) to meet industry specifications, ensuring it performs reliably in applications like catalysis or coatings. 

Here are the typical tests performed:

1. Identity & Purity Tests:

·       Assay (Zirconium Content): Determined by complexometric titration with EDTA, verifying the percentage of ZrOCl₂·8H₂O.

·       FTIR Spectroscopy: Used to confirm the chemical fingerprint and structure of the compound.

·       Loss on Drying/Water Content: Checks for proper hydration, as it can easily lose water to form the hexahydrate. 

2. Impurity Limits (Often by ACS Grade Standards):

·       Heavy Metals: Testing for overall heavy metal content.

·       Iron (Fe): Quantified to ensure low levels, often with the ammonium thiocyanate method.

·       Titanium (Ti): Checked to ensure it doesn't interfere with zirconium applications.

·       Sulfate (SO₄²⁻): Measured to control residual sulfate. 

3. Physical Properties:

·       Appearance: Visual inspection (e.g., white crystals).

·       pH of Solution: Testing the pH of a standard solution to confirm expected acidity. 

What are the challenges in Manufacturing of Banana Extract Manufactured by MEDIOCON   INC API?

Manufacturing banana extract as an API by a company like MEDIOCON INC faces general API challenges: ensuring purity & consistency, scaling up complex extractions, managing raw material supply (banana availability/quality), controlling impurities, meeting strict global regulatory compliance, optimizing cost-effective downstream processing (purification), and addressing environmental/sustainability concerns. Specific hurdles include efficiently extracting desired bioactive compounds (like flavonoids) while minimizing unwanted plant matter and ensuring a reliable, high-quality biomass source from banana cultivation. 

Key Challenges in Banana Extract API Manufacturing:

1.    Raw Material Variability & Supply:

·       Inconsistent Biomass: Bananas are agricultural products, meaning factors like weather, soil, and variety affect the nutrient and active compound content in the biomass (pseudostem, peel, etc.).

·       Sustainable Sourcing: Ensuring a continuous, high-quality, and sustainable supply of banana biomass (often waste material) can be challenging.

2.    Extraction & Purification Complexity (Downstream Processing):

·       Complex Chemistry: Extracting specific beneficial compounds (bioactives, sugars) from the plant matrix involves complex separation processes.

·       Yield vs. Purity: Achieving high yields of the target compound while maintaining high purity (removing unwanted plant matter, pigments, etc.) is a significant technical hurdle.

·       Scale-Up Issues: Processes that work in the lab may behave differently (new impurities, lower yields) at industrial scale, requiring extensive optimization.

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What are the challenges in manufacturing of ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON  INC ’s Dosage forms?

Manufacturing ZIRCONYL CHLORIDE OCTAHYDRATE,dosage forms comes with several challenges, including¹ ² ³:

- Stability Issues: Ensuring the stability of ZIRCONYL CHLORIDE OCTAHYDRATE,throughout the manufacturing process and shelf life.

- Poor Solubility: Calcium succinate's solubility can be a challenge, affecting bioavailability.

- Raw Material Sourcing: Sourcing high-quality ZIRCONYL CHLORIDE OCTAHYDRATE,and excipients can be difficult.

- Regulatory Compliance: Meeting stringent regulatory requirements for excipient manufacturing, transportation, and storage.

- Quality Assurance: Ensuring integrity and purity throughout the supply chain.

- Cost and Supply Chain Management: Balancing cost considerations with high-quality excipients.

- Manufacturing Process Failures: Deficiencies in manufacturing processes can lead to defective products.

- Particle Aggregation: Solid particles can aggregate, causing sedimentation and inconsistent dosing.

To overcome these challenges, manufacturers can leverage advanced technologies, such as 3D printing and nanotechnology, and collaborate with regulatory agencies and excipient suppliers·  Purity and Impurity Removal: Achieving high purity is difficult due to the presence of trace elements in raw zircon, such as iron, titanium, and sodium. The removal of sodium ions (

Na+Na raised to the positive power

Na+

) during the transition process is particularly challenging and can affect final product quality.

·  Stability and pH Sensitivity: Zirconyl chloride solutions are not stable; their pH decreases shortly after preparation. Maintaining a stable pH is crucial for process reproducibility and product stability, especially when incorporating it into specific dosage forms or formulations.

·  Corrosiveness: The compound is strongly acidic and corrosive in solution, demanding the use of appropriate protective equipment and corrosion-resistant manufacturing vessels.

·  Handling Issues: When processing solutions, high concentrations or rapid changes in conditions (like water addition to alcoholic solutions) can lead to highly viscous solutions or the formation of solid crystalline masses that are difficult to handle and filter.

·  Byproduct Management and Environmental Concerns: The primary industrial production methods (like the alkali fusion method) generate significant amounts of waste acid, waste alkali, and waste residue ("three wastes"), posing a major environmental challenge and increasing disposal costs..

What is the Packing for ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC?

MEDIOCON INC's Zirconyl Chloride Octahydrate (ZrOCl₂·8H₂O) is typically packed in drums (25 kg) for industrial grades, or smaller plastic containers (50g, 100g, 500g) for lab/high-purity grades, often using HDPE bottles or plastic packaging for solid forms, reflecting common industry standards for this moisture-sensitive chemical. 

Typical Packaging Details:

·       Industrial Grade: 25 kg drums, often fiber drums or HDPE drums.

·       Laboratory/High Purity: Smaller plastic bottles (e.g., 50g, 100g, 500g), often HDPE.

·       Material: Plastic containers (polyethylene) or drums to protect from moisture. 

Why this Packaging?
Zirconyl chloride octahydrate is a crystalline solid that readily absorbs moisture and can degrade, so robust, sealed packaging is essential to maintain its purity and stability. 

To Confirm MEDIOCON INC Specifics:
For exact packaging details from MEDIOCON INC, you would typically:

·       Check their official product page or website.

·       Look at an IndiaMART listing for their specific product.

·       Contact their sales or technical support directly. 

What is shelf life Of ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC? 

While specific data for Mediocon Inc. isn't shown, Zirconyl Chloride Octahydrate (ZrOCl2·8H2O) generally has a shelf life of 1 to 5 years, depending on purity and storage, with hygroscopic properties requiring storage in cool, dry conditions to maintain stability, but the manufacturer's Certificate of Analysis (COA) or product literature provides the definitive date for that specific batch. 

General Shelf Life & Stability:

·       Typical Range: Many suppliers list shelf lives from 12 months (1 year) to 5 years (60 months).

·       Hygroscopic Nature: This chemical absorbs moisture from the air, so proper sealed storage is crucial for longevity.

·       Factors Influencing Shelf Life: Purity (e.g., extra pure vs. technical grade) and adherence to recommended storage conditions (cool, dry, away from oxidizers) significantly affect stability. 

How to Find Your Specific Shelf Life:

1.    Check the COA: Look for an expiration or retest date on the Certificate of Analysis (COA) that came with your Mediocon Inc. product.

2.    Contact Mediocon Inc.: If not on the COA, contact Mediocon Inc. directly or refer to their product documentation. 

What should the label claim for ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC   Include?

·       Product Name: Zirconyl Chloride Octahydrate (or Zirconium Oxychloride Octahydrate).

·       Manufacturer: MEDIOCON INC [User Input].

·       CAS Number: 13520-92-8.

·       Molecular Formula: ZrOCl₂·8H₂O.

·       Molecular Weight: 322.25 g/mol. 

2. Hazard Identification (GHS):

·       Pictograms: Corrosion (GHS05) and Exclamation Mark (GHS07).

·       Signal Word: Danger.

·       Hazard Statements (H-Statements):

o   H318: Causes serious eye damage.

o   H314: Causes severe skin burns and eye damage.

o   H302: Harmful if swallowed.

·       Precautionary Statements (P-Statements):

o   P280: Wear protective gloves/protective clothing/eye protection/face protection.

o   P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

o   P310: Immediately call a POISON CENTER or doctor/physician.

o   P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. 

Where can ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC are procured?

ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC   can be procured from various sources, depending on your location and requirements. Here are some options:

FOR API

MEDIOCON INC

Add: B-2, ARCH SARTHAK BUILDING, N-7 CIDCO

CHATRAPATI SAMBHAJI NAGAR-431003, MAHARASHTRA, INDIA

Mob/Whatsapp No: +91-8007719681, +91-9309999757, +91-9834786939

Sales Department: Email: sales@mediocon.com

Purchase Department: Email: purchase@mediocon.com

Marketing Department: Email: mktg@mediocon.com

HR Department: Email: hr@mediocon.com

Accounts Department: Email: accounts@mediocon.com          

Factory Address: Plot No 11, Shendra MIDC, Aurangabad-431154, Maharashtra, India Website:  www.mediocon.com 

Email id:info@mediocon.com           

GST No: 27DHUPM2366D1ZZ

For Dosage Forms :

- Online Marketplaces: You can find ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC   products on online marketplaces like Amazon or e- commerce websites specializing in pharmaceuticals or skincare products.

Local Pharmacies or Skincare Stores: You can also check with local pharmacies or skincare stores in your area for ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC products.

Remember to ensure the quality and authenticity of the ZIRCONYL CHLORIDE OCTAHYDRATE,Manufactured by MEDIOCON INC product, regardless of the procurement source.